Safety, tolerability, and pharmacokinetics of repeated oral doses of 2-hydroxybenzylamine acetate in healthy volunteers: a double-blind, randomized, placebo-controlled clinical trial

被引：0
|
作者：
Lisa M. Pitchford
Patricia M. Driver
John C. Fuller
Wendell S. Akers
Naji N. Abumrad
Venkataraman Amarnath
Ginger L. Milne
Sheau-Chiann Chen
Fei Ye
L. Jackson Roberts
M. Benjamin Shoemaker
John A. Oates
John A. Rathmacher
Olivier Boutaud
机构：
[1] MTI BioTech,Department of Kinesiology
[2] Inc.,Department of Medicine, Division of Clinical Pharmacology
[3] Iowa State University,Department of Pharmaceutical Sciences
[4] Vanderbilt University Medical Center,Department of Pharmacology, Division of Clinical Pharmacology
[5] Lipscomb University College of Pharmacy,Department of Surgery
[6] Vanderbilt University,Department of Biostatistics
[7] Vanderbilt University Medical Center,Department of Medicine, Division of Cardiology
[8] Vanderbilt University Medical Center,Department of Animal Science
[9] Vanderbilt University Medical Center,undefined
[10] Iowa State University,undefined
来源：
BMC Pharmacology and Toxicology | / 21卷
关键词：
Safety; Pharmacokinetics; Humans; Salicylamine; γ-Ketoaldehydes;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] Safety, tolerability, and pharmacokinetics of repeated oral doses of 2-hydroxybenzylamine acetate in healthy volunteers: a double-blind, randomized, placebo-controlled clinical trial
    Pitchford, Lisa M.
    Driver, Patricia M.
    Fuller, John C., Jr.
    Akers, Wendell S.
    Abumrad, Naji N.
    Amarnath, Venkataraman
    Milne, Ginger L.
    Chen, Sheau-Chiann
    Ye, Fei
    Roberts, L. Jackson, II
    Shoemaker, M. Benjamin
    Oates, John A.
    Rathmacher, John A.
    Boutaud, Olivier
    BMC PHARMACOLOGY & TOXICOLOGY, 2020, 21 (01):
  • [2] A Randomized, Placebo-Controlled, Double-Blind Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Repeated Doses of Mirogabalin in Healthy Asian Volunteers
    Jansen, Mendel
    Warrington, Steven
    Dishy, Victor
    Ohwada, Shoichi
    Johnson, Lisa
    Brown, Karen
    Ishizuka, Hitoshi
    CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2018, 7 (06): : 661 - 669
  • [3] A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Ascending Multiple Oral Doses of CC 930 in Healthy Volunteers
    Kong, Linghui
    Ye, Ying
    Liu, Liangang
    Reyes, Josephine
    Wan, Yuntao
    Wu, Anfan
    Lau, Henry
    Laskin, Oscar
    JOURNAL OF CLINICAL PHARMACOLOGY, 2011, 51 (09): : 1343 - 1343
  • [4] Safety, Tolerability, and Pharmacokinetics of β-Cryptoxanthin Supplementation in Healthy Women: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial
    Tan, Karen M. L.
    Chee, Jolene
    Lim, Kezlyn L. M.
    Ng, Maisie
    Gong, Min
    Xu, Jia
    Tin, Felicia
    Natarajan, Padmapriya
    Lee, Bee Lan
    Ong, Choon Nam
    Tint, Mya Thway
    Kee, Michelle Z. L.
    Muller-Riemenschneider, Falk
    Gluckman, Peter D.
    Meaney, Michael J.
    Kumar, Mukkesh
    Karnani, Neerja
    Eriksson, Johan G.
    Nandanan, Bindu
    Wyss, Adrian
    Cameron-Smith, David
    NUTRIENTS, 2023, 15 (10)
  • [5] Cardiovascular safety and pharmacokinetics of almotriptan:: a randomized, double-blind, placebo-controlled, crossover clinical trial in healthy volunteers
    Salvà, M
    Jansat, JM
    Martínez-Tobed, A
    CEPHALALGIA, 2003, 23 (07) : 706 - 706
  • [6] Phase 1, Randomized, Double-Blind, Placebo-Controlled Studies of the Safety, Tolerability and Pharmacokinetics of Naldemedine in Healthy Volunteers
    Fukumura, Kazuya
    Yokota, Takaaki
    Baba, Yuko
    Camilo, Juan
    Ferreira, Arjona
    GASTROENTEROLOGY, 2016, 150 (04) : S537 - S538
  • [7] Phase 1, Randomized, Double-Blind, Placebo-Controlled Studies on the Safety, Tolerability, and Pharmacokinetics of Naldemedine in Healthy Volunteers
    Fukumura, Kazuya
    Yokota, Takaaki
    Baba, Yuko
    Ferreira, Juan Camilo Arjona
    CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2018, 7 (05): : 474 - 483
  • [8] A Double-Blind, Placebo-Controlled Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of JDTic
    Jeffrey J Buda
    F I Carroll
    Thomas R Kosten
    Dennis Swearingen
    Bradford B Walters
    Neuropsychopharmacology, 2015, 40 : 2059 - 2065
  • [9] A Double-Blind, Placebo-Controlled Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of JDTic
    Buda, Jeffrey J.
    Carroll, F. I.
    Kosten, Thomas R.
    Swearingen, Dennis
    Walters, Bradford B.
    NEUROPSYCHOPHARMACOLOGY, 2015, 40 (09) : 2059 - 2065
  • [10] Safety, tolerability, and pharmacokinetics of ibrexafungerp in healthy Chinese subjects: a randomized, double-blind, placebo-controlled phase 1 trial
    Liu, Xiaoyan
    Zhang, Rui
    Li, Rong
    Wu, Qiong
    Pan, Chao
    Yu, Xiangqing
    Liu, Yuhui
    Wang, Benjie
    Yu, Shuwen
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2023, 67 (12)
12345