Freeze-Dried Biopharmaceutical Formulations are Surprisingly Less Stable than Liquid Formulations during Dropping

被引：0
|
作者：
Wei-Jie Fang
Meng-Juan Pang
Jia-Wei Liu
Xinyu Wang
Haibin Wang
Min-Fei Sun
机构：
[1] Zhejiang University,Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences
[2] Zhejiang University,Hangzhou Institute of Innovative Medicine
[3] Zhejiang University,Department of Chemistry
[4] Zhejiang Bioray Biopharmaceutical Co,undefined
来源：
Pharmaceutical Research | 2022年 / 39卷
关键词：
biopharmaceutical formulation; dropping; free radical; freeze-dry; protein aggregation; specific heat capacity; sub-visible particle;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：795 / 803
页数：8
相关论文
共 50 条
  • [1] Freeze-Dried Biopharmaceutical Formulations are Surprisingly Less Stable than Liquid Formulations during Dropping
    Fang, Wei-Jie
    Pang, Meng-Juan
    Liu, Jia-Wei
    Wang, Xinyu
    Wang, Haibin
    Sun, Min-Fei
    PHARMACEUTICAL RESEARCH, 2022, 39 (04) : 795 - 803
  • [2] Physical characterisation of formulations for the development of two stable freeze-dried proteins during both dried and liquid storage
    Passot, S
    Fonseca, F
    Alarcon-Lorca, M
    Rolland, D
    Marin, M
    EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2005, 60 (03) : 335 - 348
  • [3] Freeze-Dried Monoclonal Antibody Formulations are Unexpectedly More Prone to Degradation Than Liquid Formulations Under Shaking Stress
    Fang, Wei-Jie
    Ingle, Rahul G.
    Liu, Jia-Wei
    Ge, Xin-Zhe
    Wang, Haibin
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2022, 111 (07) : 2134 - 2138
  • [4] Equivalence of liquid and freeze-dried formulations of WinRho® SDF.
    Sinclair, CJ
    Ruckle, J
    Swearingen, D
    Kisicki, JC
    Marbury, TC
    Genereux, M
    Brooks, W
    BLOOD, 2005, 106 (11) : 76B - 77B
  • [5] Effects of Secondary Package on Freeze-Dried Biopharmaceutical Formulation Stability During Dropping
    Fang, Wei-Jie
    Liu, Jia-Wei
    Barnard, James
    Wang, Haibin
    Qian, Yan-Chen
    Xu, Jie
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 110 (08) : 2916 - 2924
  • [6] Excipients for Room Temperature Stable Freeze-Dried Monoclonal Antibody Formulations
    Haeuser, Christina
    Goldbach, Pierre
    Huwyler, Joerg
    Friess, Wolfgang
    Allmendinger, Andrea
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2020, 109 (01) : 807 - 817
  • [7] The bioequivalence of liquid and freeze-dried formulations of recombinant human chorionic gonadotrophin
    van der Merwe, R
    Lugan, I
    Lecuelle, H
    Papasouliotis, O
    Buraglio, M
    CURRENT MEDICAL RESEARCH AND OPINION, 2004, 20 (03) : 397 - 402
  • [8] Screening of novel excipients for freeze-dried protein formulations
    Holm, Tobias Palle
    Meng-Lund, Helena
    Rantanen, Jukka
    Jorgensen, Lene
    Grohganz, Holger
    EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2021, 160 : 55 - 64
  • [9] Influence of water and trehalose on α - and β -relaxation of freeze-dried lysozyme formulations
    Vallaster, Bernadette
    Engelsing, Florian
    Grohganz, Holger
    EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2024, 194 : 1 - 8
  • [10] Investigation of the stabilisation of freeze-dried lysozyme and the physical properties of the formulations
    Liao, YH
    Brown, MB
    Martin, GP
    EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2004, 58 (01) : 15 - 24
12345