Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor

被引:0
|
作者
William J. Zacharias
David B. Frank
Jarod A. Zepp
Michael P. Morley
Farrah A. Alkhaleel
Jun Kong
Su Zhou
Edward Cantu
Edward E. Morrisey
机构
[1] University of Pennsylvania,Department of Medicine
[2] Penn Center for Pulmonary Biology,Department of Pediatrics
[3] University of Pennsylvania,Department of Surgery
[4] Children’s Hospital of Philadelphia,Department of Cell and Developmental Biology
[5] Penn Cardiovascular Institute,undefined
[6] University of Pennsylvania,undefined
[7] University of Pennsylvania,undefined
[8] University of Pennsylvania,undefined
[9] Philadelphia,undefined
[10] Penn Institute for Regenerative Medicine,undefined
[11] University of Pennsylvania,undefined
来源
Nature | 2018年 / 555卷
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学科分类号
摘要
An evolutionarily conserved alveolar epithelial progenitor lineage that derives from alveolar type 2 cells is responsive to Wnt signalling and acts as a major facultative progenitor in regenerating the distal lung.
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页码:251 / 255
页数:4
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