Isoquercetin regulates SREBP-1C via AMPK pathway in skeletal muscle to exert antihyperlipidemic and anti-inflammatory effects in STZ induced diabetic rats

被引：0
|
作者：
Muthukumaran Jayachandran
Tongze Zhang
Ziyuan Wu
Yinhua Liu
Baojun Xu
机构：
[1] Beijing Normal University-Hong Kong Baptist University United International College,Food Science and Technology Program
[2] Zhuhai Campus of the Zunyi Medical University,Biomedicine Research and Development Center
来源：
Molecular Biology Reports | 2020年 / 47卷
关键词：
Streptozotocin; Hyperlipidemia; HMG-Co-A; AMPK-α; SREBP-1C;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：593 / 602
页数：9
相关论文
共 50 条
  • [1] Isoquercetin regulates SREBP-1C via AMPK pathway in skeletal muscle to exert antihyperlipidemic and anti-inflammatory effects in STZ induced diabetic rats
    Jayachandran, Muthukumaran
    Zhang, Tongze
    Wu, Ziyuan
    Liu, Yinhua
    Xu, Baojun
    MOLECULAR BIOLOGY REPORTS, 2020, 47 (01) : 593 - 602
  • [2] Isosilybin regulates lipogenesis and fatty acid oxidation via the AMPK/SREBP-1c/PPARα pathway
    Liu, Xueyun
    Hu, Man
    Ye, Chen
    Liao, Lihong
    Ding, Chang
    Sun, Lijuan
    Liang, Jichao
    Chen, Yong
    CHEMICO-BIOLOGICAL INTERACTIONS, 2022, 368
  • [3] Isoquercetin upregulates antioxidant genes, suppresses inflammatory cytokines and regulates AMPK pathway in streptozotocin-induced diabetic rats
    Jayachandran, Muthukumaran
    Wu, Ziyuan
    Ganesan, Kumar
    Khalid, Sumbul
    Chung, S. M.
    Xu, Baojun
    CHEMICO-BIOLOGICAL INTERACTIONS, 2019, 303 : 62 - 69
  • [4] Suppression of Rho-kinase 1 is responsible for insulin regulation of the AMPK/SREBP-1c pathway in skeletal muscle cells exposed to palmitate
    Tang, Sunyinyan
    Wu, Wenjun
    Tang, Wenjuan
    Ge, Zhijuan
    Wang, Hongdong
    Hong, Ting
    Zhu, Dalong
    Bi, Yan
    ACTA DIABETOLOGICA, 2017, 54 (07) : 635 - 644
  • [5] Suppression of Rho-kinase 1 is responsible for insulin regulation of the AMPK/SREBP-1c pathway in skeletal muscle cells exposed to palmitate
    Sunyinyan Tang
    Wenjun Wu
    Wenjuan Tang
    Zhijuan Ge
    Hongdong Wang
    Ting Hong
    Dalong Zhu
    Yan Bi
    Acta Diabetologica, 2017, 54 : 635 - 644
  • [6] Suppression of Rho-kinase 1 is responsible for insulin regulation of the AMPK/SREBP-1c pathway in skeletal muscle cells exposed to palmitate
    Sun, Yinyantang
    Wu, Wenjun
    Tang, Wenjuan
    Ge, Zhijuan
    Hong, Ting
    Zhu, Dalong
    Bi, Yan
    DIABETES-METABOLISM RESEARCH AND REVIEWS, 2016, 32 (SUPP 2) : 10 - 10
  • [7] Alisol A attenuates high-fat-diet-induced obesity and metabolic disorders via the AMPK/ACC/SREBP-1c pathway
    Ho, Chiakang
    Gao, Ya
    Zheng, Danning
    Liu, Yanjun
    Shan, Shengzhou
    Fang, Bin
    Zhao, Yixuan
    Song, Dingzhong
    Zhang, Yifan
    Li, Qingfeng
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 23 (08) : 5108 - 5118
  • [8] Role for SREBP-1c in inducing skeletal muscle insulin resistance via repressing IRS-1 transcription and promoting inflammatory response
    Bi, Y.
    Chen, Y.
    Wu, W.
    Cai, M.
    Liang, H.
    Zhu, D.
    DIABETOLOGIA, 2013, 56 : S78 - S79
  • [9] ANTIDIABETIC AND ANTI-INFLAMMATORY ACTIVITY OF UTICA DIOICA LEAVES ON STZ INDUCED TYPE 1 DIABETIC MODEL RATS
    Morshed, M. A.
    Alam, J.
    Das, M.
    Haque, A.
    Ali, L.
    Rokeya, B.
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2011, 2 (05): : 1182 - 1187
  • [10] Anti-Apoptotic and Anti-Inflammatory Effects of Ginger Extract on Small Intestine Tissue in STZ-Induced Diabetic Rats
    Bakir, Buket
    KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI, 2023, 29 (04) : 391 - 399
12345