Synthesis and biological activity of substituted 2-iminobenzo[f]coumarin-3- carboxylic acid amides

被引：0
|
作者：
Ukhov S.V. [1 ]
Syropyatov B.Ya. [1 ]
Novikova V.V. [1 ]
Balabash V.A. [1 ]
Shustov A.S. [1 ]
Odegova T.F. [1 ]
机构：
[1] Perm State Pharmaceutical Academy, Perm
来源：
Pharmaceutical Chemistry Journal | 2011年 / 45卷 / 4期
关键词：
2-iminobenzo[f]coumarin-3-carboxylic acid; Amides; anticoagulant and antimicrobial activities; synthesis;
D O I：
10.1007/s11094-011-0601-3
中图分类号：
学科分类号：
摘要：
Interaction of 2-hydroxynaphthaline-1-carbaldehyde with cyanoacetic acid arylamides was used to synthesize substituted 2-iminobenzo[f]coumarin-3- carboxylic acid amides. Heating of substituted 2-iminobenzo[f]coumarin-3- carboxylic acid amides with acetic anhydride led to the synthesis of acetyl derivatives of this acid. The anticoagulant and antimicrobial activities of these compounds were studied. © 2011 Springer Science+Business Media, Inc.
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页码：228 / 230
页数：2
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