Golgi fragmentation precedes neuromuscular denervation and is associated with endosome abnormalities in SOD1-ALS mouse motor neurons

被引：0
|
作者：
Vera van Dis
Marijn Kuijpers
Elize D Haasdijk
Eva Teuling
Scott A Oakes
Casper C Hoogenraad
Dick Jaarsma
机构：
[1] Erasmus Medical Center,Department of Neuroscience
[2] Utrecht University,Cell Biology, Faculty of Science
[3] University of California,Department of Pathology
来源：
Acta Neuropathologica Communications | / 2卷
关键词：
Amyotrophic Lateral Sclerosis (ALS); Protein aggregation; Endosome trafficking; Dynein; Transgenic mouse model; SOD1;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 16 条
  • [1] Golgi fragmentation precedes neuromuscular denervation and is associated with endosome abnormalities in SOD1-ALS mouse motor neurons
    van Dis, Vera
    Kuijpers, Marijn
    Haasdijk, Elize D.
    Teuling, Eva
    Oakes, Scott A.
    Hoogenraad, Casper C.
    Jaarsma, Dick
    ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2014, 2
  • [2] A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice
    Teuling, Eva
    van Dis, Vera
    Wulf, Phebe S.
    Haasdijk, Elize D.
    Akhmanova, Anna
    Hoogenraad, Casper C.
    Jaarsma, Dick
    HUMAN MOLECULAR GENETICS, 2008, 17 (18) : 2849 - 2862
  • [3] Stathmin 1/2-triggered microtubule loss mediates Golgi fragmentation in mutant SOD1 motor neurons
    Bellouze, Sarah
    Baillat, Gilbert
    Buttigieg, Dorothee
    de la Grange, Pierre
    Rabouille, Catherine
    Haase, Georg
    MOLECULAR NEURODEGENERATION, 2016, 11
  • [4] Stathmin 1/2-triggered microtubule loss mediates Golgi fragmentation in mutant SOD1 motor neurons
    Sarah Bellouze
    Gilbert Baillat
    Dorothée Buttigieg
    Pierre de la Grange
    Catherine Rabouille
    Georg Haase
    Molecular Neurodegeneration, 11
  • [5] Development of abnormalities at the neuromuscular junction in the SOD1-G93A mouse model of ALS: dysfunction then disruption of postsynaptic structure precede overt motor symptoms
    McIntosh, Jayne
    Mekrouda, Imane
    Dashti, Maryam
    Giuraniuc, Claudiu V.
    Banks, Robert W.
    Miles, Gareth B.
    Bewick, Guy S.
    FRONTIERS IN MOLECULAR NEUROSCIENCE, 2023, 16
  • [6] In vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model
    Yi A. Chen
    Mark W. Kankel
    Sam Hana
    Shukkwan Kelly Lau
    Maria I. Zavodszky
    Olivia McKissick
    Nicole Mastrangelo
    Jessica Dion
    Bin Wang
    Daniel Ferretti
    David Koske
    Sydney Lehman
    Kathryn Koszka
    Helen McLaughlin
    Mei Liu
    Eric Marshall
    Attila J. Fabian
    Patrick Cullen
    Galina Marsh
    Stefan Hamann
    Michael Craft
    Jennifer Sebalusky
    H. Moore Arnold
    Rachelle Driscoll
    Adam Sheehy
    Yi Luo
    Sonia Manca
    Thomas Carlile
    Chao Sun
    Kirsten Sigrist
    Alexander McCampbell
    Christopher E. Henderson
    Shih-Ching Lo
    Gene Therapy, 2023, 30 : 443 - 454
  • [7] In vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model
    Chen, Yi A. A.
    Kankel, Mark W. W.
    Hana, Sam
    Lau, Shukkwan Kelly
    Zavodszky, Maria I. I.
    McKissick, Olivia
    Mastrangelo, Nicole
    Dion, Jessica
    Wang, Bin
    Ferretti, Daniel
    Koske, David
    Lehman, Sydney
    Koszka, Kathryn
    McLaughlin, Helen
    Liu, Mei
    Marshall, Eric
    Fabian, Attila J. J.
    Cullen, Patrick
    Marsh, Galina
    Hamann, Stefan
    Craft, Michael
    Sebalusky, Jennifer
    Arnold, H. Moore
    Driscoll, Rachelle
    Sheehy, Adam
    Luo, Yi
    Manca, Sonia
    Carlile, Thomas
    Sun, Chao
    Sigrist, Kirsten
    McCampbell, Alexander
    Henderson, Christopher E. E.
    Lo, Shih-Ching
    GENE THERAPY, 2023, 30 (05) : 443 - 454
  • [8] RNA-Seq Profiling of Spinal Cord Motor Neurons from a Presymptomatic SOD1 ALS Mouse
    Bandyopadhyay, Urmi
    Cotney, Justin
    Nagy, Maria
    Oh, Sunghee
    Leng, Jing
    Mahajan, Milind
    Mane, Shrikant
    Fenton, Wayne A.
    Noonan, James P.
    Horwich, Arthur L.
    PLOS ONE, 2013, 8 (01):
  • [9] In Vivo Genome Editing Using Novel AAV-PHP Variants Rescues Motor Function Deficits and Extends Survival in a SOD1-ALS Mouse Model
    Lo, Shih-Ching
    MOLECULAR THERAPY, 2021, 29 (04) : 283 - 284
  • [10] ALS associated mutant SOD1 impairs the motor neurons and astrocytes and wild type astrocyte secreted-factors reverse the impaired motor neurons
    Rajan, Thangavelu Soundara
    Tripathi, Prem Prakash
    Arya, Upasna
    Mishra, Himanshu K.
    Subramaniam, Jamuna R.
    ANNALS OF NEUROSCIENCES, 2011, 18 (02) : 48 - 55
12