The influence of neoadjuvant chemotherapy on breast conserving therapy and post-mastectomy radiation therapy

被引：0
|
作者：
Zellars R.C. [1 ]
机构：
[1] Radiation Oncology and Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD 21231
来源：
Current Breast Cancer Reports | 2011年 / 3卷 / 4期
关键词：
Breast cancer; Breast conserving therapy; Neoadjuvant chemotherapy; Post-mastectomy; Pre-operative chemotherapy; Primary chemotherapy; Radiation therapy;
D O I：
10.1007/s12609-011-0058-0
中图分类号：
学科分类号：
摘要：
Neoadjuvant chemotherapy (NACT) has revolutionized the management of women with locally advanced breast cancer. Although this change in treatment paradigm has facilitated surgery and helped to predict outcomes in certain subsets of patients, it has also caused some confusion with respect to the role of adjuvant radiation therapy. This review discusses the benefits of NACT, the questions that arose as a result of this change in sequence, and, using the current literature, the possible answers to these questions. The reader should leave this review with a basic understanding of the issues faced by the radiation oncologist when consulting patients who have been treated with NACT. © 2011 Springer Science+Business Media, LLC.
引用
收藏
页码：220 / 224
页数：4
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