The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases

被引：0
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作者：
Cheol-Sang Hwang
Anna Shemorry
Daniel Auerbach
Alexander Varshavsky
机构：
[1] California Institute of Technology,Division of Biology
[2] Dualsystems Biotech AG,undefined
来源：
Nature Cell Biology | 2010年 / 12卷
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摘要：
Two pathways in ubiquitylation are linked, as the RING domain E3 ligase Ubr1, from the N-end rule pathway, is found to bind and cooperate with the HECT domain E3 Ufd4 from the ubiquitin-fusion degradation pathway.
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页码：1177 / 1185
页数：8
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