The transcription factor Foxm1 is essential for the quiescence and maintenance of hematopoietic stem cells

被引：0
|
作者：
Yu Hou
Wen Li
Yue Sheng
Liping Li
Yong Huang
Zhonghui Zhang
Tongyu Zhu
David Peace
John G Quigley
Wenshu Wu
You-yang Zhao
Zhijian Qian
机构：
[1] The University of Illinois Hospital and Health Sciences System,Department of Medicine and Cancer Research Center
[2] Fudan University ZhongShan Hospital,Department of Medicine
[3] Section of Gastroenterology,Department of Pharmocology
[4] The University of Chicago,undefined
[5] The University of Illinois Hospital and Health Sciences System,undefined
来源：
Nature Immunology | 2015年 / 16卷
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摘要：
Hematopoietic stem cells are held in check to maintain their functional activity throughout life. Qian and colleagues show that the transcriptional regulator Foxm1 maintains the quiescence and self-renewal capacity of these cells in vivo.
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页码：810 / 818
页数：8
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