CRD-BP mediates stabilization of βTrCP1 and c-myc mRNA in response to β-catenin signalling

被引:0
|
作者
Felicite K. Noubissi
Irina Elcheva
Neehar Bhatia
Abbas Shakoori
Andrei Ougolkov
Jianghuai Liu
Toshinari Minamoto
Jeff Ross
Serge Y. Fuchs
Vladimir S. Spiegelman
机构
[1] University of Wisconsin School of Medicine and Public Health,Department of Dermatology
[2] Cancer Research Institute,Division of Translational and Clinical Oncology
[3] Kanazawa University,Department of Animal Biology
[4] University of Pennsylvania,McArdle Laboratory for Cancer Research
[5] University of Wisconsin School of Medicine and Public Health,Division of Oncology Research
[6] Mayo Clinic,undefined
来源
Nature | 2006年 / 441卷
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中图分类号
学科分类号
摘要
β-catenin stabilizes the mRNA encoding the F-box protein βTrCP1, and the RNA-binding protein CRD–BP (coding region determinant-binding protein) is identified as a previously unknown target of β-catenin/Tcf transcription factor.
引用
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页码:898 / 901
页数:3
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