Preparation and characterization of nanocomposite polyvinyl chloride films with NO-generating activity

被引:0
|
作者
Roman B. Kozakevych
Alina V. Korobeinyk
Yulia M. Bolbukh
Valentin A. Tertykh
Lyuba I. Mikhalovska
Malgorzlata Zienkiewicz-Strzałka
Anna Deryło-Marczewska
机构
[1] National Academy of Sciences of Ukraine,Chuiko Institute of Surface Chemistry
[2] University of Brighton,undefined
[3] Pharmacy and Biomolecular Sciences,undefined
[4] Maria Curie Skłodowska University,undefined
来源
Applied Nanoscience | 2019年 / 9卷
关键词
Nanoparticles; Polyvinyl chloride (PVC); NO release; -nitrosoglutathione; Composite film; Catalytic activity;
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中图分类号
学科分类号
摘要
The silica and copper oxide nanoparticles were embedded into the polyvinyl chloride film and obtained filled composites were tested as a catalyst in the reaction of the NO release from appropriate biomolecules. Obtained materials were characterized using scanning electron, atomic-force microscopies and thermomechanical analysis. It has been shown that the introduced particles are distributed uniformly in the polymeric matrix of hybrid composite and such film produces a significant amount of NO when reacts with S-nitrosothiols. At the same time, the unfilled polyvinyl chloride film had no statistically significant catalytic activity.
引用
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页码:801 / 808
页数:7
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