Effect of sleep deprivation on the growth hormone response to the alpha-2 adrenergic receptor agonist, clonidine, in normal subjects

被引:0
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作者
S. Lal
J. X. Thavundayil
B. Krishnan
N. P. V. Nair
G. Schwartz
M. E. Kiely
H. Guyda
机构
[1] Douglas Hospital Research Centre,Department of Psychiatry
[2] Montreal General Hospital,Protein and Polypeptide Laboratory
[3] McGill University,undefined
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关键词
Sleep deprivation; clonidine; growth hormone; adrenergic receptor;
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摘要
One night's sleep deprivation (SD) increased the growth hormone (GH) response to clonidine (2 ug/kg iv) in 11 normal men (p < 0.005). This finding may indicate that SD enhances alpha-2 adrenergic receptor function or that the GH response to GH releasing factor is increased by SD.
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页码:291 / 298
页数:7
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