A massively parallel reporter assay dissects the influence of chromatin structure on cis-regulatory activity

被引：0
|
作者：
Brett B Maricque
Hemangi G Chaudhari
Barak A Cohen
机构：
[1] The Edison Family Center for Genome Sciences and Systems Biology,Department of Genetics
[2] Washington University School of Medicine,undefined
[3] Washington University School of Medicine,undefined
[4] Present address: Department of Biological Sciences,undefined
[5] Howard Hughes Medical Institute,undefined
[6] Columbia University,undefined
[7] New York,undefined
[8] New York,undefined
[9] USA.,undefined
来源：
Nature Biotechnology | 2019年 / 37卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A genome-wide assay defines the relationship of cis-regulatory sequences and chromatin structure in regulating gene expression.
引用
收藏
页码：90 / 95
页数：5
相关论文
共 50 条
  • [1] A massively parallel reporter assay dissects the influence of chromatin structure on cis-regulatory activity
    Maricque, Brett B.
    Chaudhari, Hemangi G.
    Cohen, Barak A.
    NATURE BIOTECHNOLOGY, 2019, 37 (01) : 90 - +
  • [2] A genome-integrated massively parallel reporter assay reveals DNA sequence determinants of cis-regulatory activity in neural cells
    Maricque, Brett B.
    Dougherty, Joseph D.
    Cohen, Barak A.
    NUCLEIC ACIDS RESEARCH, 2017, 45 (04) : e16
  • [3] Massively Parallel Reporter Assays for High-Throughput In Vivo Analysis of Cis-Regulatory Elements
    Zheng, Yanjiang
    VanDusen, Nathan J.
    JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE, 2023, 10 (04)
  • [4] High-Throughput Analysis of Retinal Cis-Regulatory Networks by Massively Parallel Reporter Assays
    Oh, Inez Y.
    Chen, Shiming
    RETINAL DEGENERATIVE DISEASES: MECHANISMS AND EXPERIMENTAL THERAPY, 2019, 1185 : 359 - 364
  • [5] Identification of cis-regulatory elements by chromatin structure
    Lu, Zefu
    Ricci, William A.
    Schmitz, Robert J.
    Zhang, Xiaoyu
    CURRENT OPINION IN PLANT BIOLOGY, 2018, 42 : 90 - 94
  • [6] Massively parallel cis-regulatory analysis in the mammalian central nervous system
    Shen, Susan Q.
    Myers, Connie A.
    Hughes, Andrew E. O.
    Byrne, Leah C.
    Flannery, John G.
    Corbo, Joseph C.
    GENOME RESEARCH, 2016, 26 (02) : 238 - 255
  • [7] Understanding how cis-regulatory function is encoded in DNA sequence using massively parallel reporter assays and designed sequences
    White, Michael A.
    GENOMICS, 2015, 106 (03) : 165 - 170
  • [8] The Role of Chromatin Accessibility in cis-Regulatory Evolution
    Peng, Pei-Chen
    Khoueiry, Pierre
    Girardot, Charles
    Reddington, James P.
    Garfield, David A.
    Furlong, Eileen E. M.
    Sinha, Saurabh
    GENOME BIOLOGY AND EVOLUTION, 2019, 11 (07): : 1813 - 1828
  • [9] Massively parallel in vivo enhancer assay reveals that highly local features determine the cis-regulatory function of ChIP-seq peaks
    White, Michael A.
    Myers, Connie A.
    Corbo, Joseph C.
    Cohen, Barak A.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 110 (29) : 11952 - 11957
  • [10] A Modular Massively Parallel Reporter Assay Uncovers Context-Specific Activity of Diabetes-Associated Regulatory Elements
    Tovar, Adelaide
    DIABETES, 2022, 71
12345