An orally delivered small-molecule formulation with antiangiogenic and anticancer activity

被引：0

作者：

Ofra Benny

Ofer Fainaru

Avner Adini

Flavia Cassiola

Lauren Bazinet

Irit Adini

Elke Pravda

Yaakov Nahmias

Samir Koirala

Gabriel Corfas

Robert J D'Amato

Judah Folkman

机构：

[1] Children's Hospital Boston,Vascular Biology Program and Department of Surgery

[2] Harvard Medical School,Department of Neurology

[3] Center for Engineering in Medicine,Department of Ophthalmology

[4] Massachusetts General Hospital,undefined

[5] Harvard Medical School,undefined

[6] F.M. Kirby Neurobiology Center,undefined

[7] Children's Hospital,undefined

[8] Harvard Medical School,undefined

[9] Harvard Medical School,undefined

[10] Children's Hospital Boston,undefined

来源：

Nature Biotechnology | 2008年 / 26卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Widespread use of antiangiogenic drugs for cancer therapy is limited in part by the requirement for intravenous injection. Benny et al. describe an oral formulation of an antiangiogenic small molecule that inhibits tumor growth and prevents liver metastases in mice.

引用

页码：799 / 807

页数：8

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