Is withdrawal-induced anxiety in alcoholism based on β-endorphin deficiency?

被引：0
|
作者：
Falk Kiefer
Mirko Horntrich
Holger Jahn
Klaus Wiedemann
机构：
[1] Department of Psychiatry,
[2] University Hospital Hamburg-Eppendorf,undefined
[3] Martinistrasse 52,undefined
[4] 20251 Hamburg,undefined
来源：
Psychopharmacology | 2002年 / 162卷
关键词：
β-Endorphin Anxiety Alcoholism Withdrawal HPA Opioid;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Rationale. Associations between several psychopathological alterations and lowered β-endorphin(βE) plasma levels have already been stated in former studies. However, whereas single measures during static conditions generally failed in linking βE levels with psychopathology, dynamic changes of βE in particular have been shown to be associated with spells of anxiety and depression. During alcohol withdrawal, a decreased secretion of βE with a delayed normalization has been reported, but up to now only few data became available regarding the interaction of plasma βE and psychopathological parameters.
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页码：433 / 437
页数：4
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