DND1 maintains germline stem cells via recruitment of the CCR4–NOT complex to target mRNAs

被引：0

作者：

Masashi Yamaji

Miki Jishage

Cindy Meyer

Hemant Suryawanshi

Evan Der

Misaki Yamaji

Aitor Garzia

Pavel Morozov

Sudhir Manickavel

Hannah L. McFarland

Robert G. Roeder

Markus Hafner

Thomas Tuschl

机构：

[1] Howard Hughes Medical Institute and Laboratory for RNA Molecular Biology,

[2] The Rockefeller University,undefined

[3] Laboratory of Biochemistry and Molecular Biology,undefined

[4] The Rockefeller University,undefined

[5] Albert Einstein College of Medicine,undefined

[6] Laboratory of Muscle Stem Cells and Gene Regulation,undefined

[7] National Institute for Arthritis and Musculoskeletal and Skin Disease,undefined

来源：

Nature | 2017年 / 543卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The vertebrate-conserved and germline-specific RNA-binding protein DND1 recruits the CCR4–NOT deadenylase complex to destabilize its mRNA targets and is required for the maintenance of germline stem cells.

引用

页码：568 / 572

页数：4

共 15 条

[1] DND1 maintains germline stem cells via recruitment of the CCR4-NOT complex to target mRNAs
Yamaji, Masashi
Jishage, Miki
Meyer, Cindy
Suryawanshi, Hemant
Evan Der
Yamaji, Misaki
Garzia, Aitor
Morozov, Pavel
Manickavel, Sudhir
Mcfarland, Hannah L.
Roeder, Robert G.
Hafner, Markus
Tuschl, Thomas
NATURE, 2017, 543 (7646) : 568 - +
[2] TSC1/2 tumour suppressor complex maintains Drosophila germline stem cells by preventing differentiation
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[4] Blockade of MCP-1/CCR4 signaling-induced recruitment of activated regulatory cells evokes an antitumor immune response in head and neck squamous cell carcinoma
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[6] Ddx56 maintains proliferation of mouse embryonic stem cells via ribosome assembly and interaction with the Oct4/Sox2 complex
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[7] Ddx56 maintains proliferation of mouse embryonic stem cells via ribosome assembly and interaction with the Oct4/Sox2 complex
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Liu, Jiahui
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STEM CELL RESEARCH & THERAPY, 2020, 11 (01)
[8] Notch3 Knockout Suppresses Mouse Mammary Gland Development and Inhibits the Proliferation of 4T1 Murine Mammary Carcinoma Cells via CCL2/CCR4 Axis
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FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, 8
[9] Leukocyte Function-Associated Antigen-1 (LFA-1) Antagonist Lifitegrast Prevents Corneal Recruitment of Effector T cells (Th1) by Modulating CXCR3 and CCR4 expression During Dry Eye Disease (DED)
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INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2022, 63 (07)
[10] HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4
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Raucci, Angela
Martinez Munoz, Laura
Livoti, Elsa
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JOURNAL OF EXPERIMENTAL MEDICINE, 2012, 209 (03): : 551 - 563

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