An Appraisal of PCR-Based Technology in the Detection of Mycobacterium tuberculosis

被引：0
|
作者：
Sathish Sankar
Mageshbabu Ramamurthy
Balaji Nandagopal
Gopalan Sridharan
机构：
[1] Sri Narayani Hospital and Research Centre,Division of Biomedical Research
来源：
Molecular Diagnosis & Therapy | 2011年 / 15卷 / 1期
关键词：
Tuberculosis; Sarcoidosis; Hsp65 Gene; National Tuberculosis Control Program; Line Probe Assay;
D O I：
10.1007/BF03257188
中图分类号：
学科分类号：
摘要：
Tuberculosis is an under-recognized yet catastrophic health problem, particularly in developing countries. The HIV pandemic has served to increase the number of susceptible individuals, and multidrug-resistance and poor socioeconomic conditions also augment the prevalence and the consequences of the disease. To control the disease and its spread, it is vital that tuberculosis diagnostics are accurate and rapid. Whereas microscopy and culture have several limitations (low sensitivity is a problem for the former, while the latter has a delayed turnaround time), PCR-based techniques targeting regions of the Mycobacterium tuberculosis genome such as IS6110 have proved to be useful.
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页码：1 / 11
页数：10
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