CYP450 phenotyping and metabolite identification of quinine by accurate mass UPLC-MS analysis: a possible metabolic link to blackwater fever

被引：0
|
作者：
Sean R Marcsisin
Xiannu Jin
Theresa Bettger
Nicholas McCulley
Jason C Sousa
G Dennis Shanks
Babu L Tekwani
Rajnish Sahu
Gregory A Reichard
Richard J Sciotti
Victor Melendez
Brandon S Pybus
机构：
[1] Walter Reed Army Institute of Research,Department of Drug Development, Division of Experimental Therapeutics
[2] Gallipoli BarracksEnoggera,Australian Army Malaria Institute
[3] University of Mississippi,National Center for Natural Products Research, School of Pharmacy
来源：
Malaria Journal | / 12卷
关键词：
Quinine; Blackwater fever; Metabolism; CYP450; Metabolite identification;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 4 条
  • [1] CYP450 phenotyping and metabolite identification of quinine by accurate mass UPLC-MS analysis: a possible metabolic link to blackwater fever
    Marcsisin, Sean R.
    Jin, Xiannu
    Bettger, Theresa
    McCulley, Nicholas
    Sousa, Jason C.
    Shanks, G. Dennis
    Tekwani, Babu L.
    Sahu, Rajnish
    Reichard, Gregory A.
    Sciotti, Richard J.
    Melendez, Victor
    Pybus, Brandon S.
    MALARIA JOURNAL, 2013, 12
  • [2] CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine
    Pybus, Brandon S.
    Sousa, Jason C.
    Jin, Xiannu
    Ferguson, James A.
    Christian, Robert E.
    Barnhart, Rebecca
    Vuong, Chau
    Sciotti, Richard J.
    Reichard, Gregory A.
    Kozar, Michael P.
    Walker, Larry A.
    Ohrt, Colin
    Melendez, Victor
    MALARIA JOURNAL, 2012, 11
  • [3] CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine
    Brandon S Pybus
    Jason C Sousa
    Xiannu Jin
    James A Ferguson
    Robert E Christian
    Rebecca Barnhart
    Chau Vuong
    Richard J Sciotti
    Gregory A Reichard
    Michael P Kozar
    Larry A Walker
    Colin Ohrt
    Victor Melendez
    Malaria Journal, 11
  • [4] GABAA receptor activity modulating piperine analogs: In vitro metabolic stability, metabolite identification, CYP450 reaction phenotyping, and protein binding
    Zabela, Volha
    Hettich, Timm
    Schlotterbeck, Gotz
    Wimmer, Laurin
    Mihovilovic, Marko D.
    Guillet, Fabrice
    Bouaita, Belkacem
    Shevchenko, Benedicte
    Hamburger, Matthias
    Oufir, Mouhssin
    JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2018, 1072 : 379 - 389
1