Inflammation in uveal melanoma

被引：0
|
作者：
I H G Bronkhorst
M J Jager
机构：
[1] Leiden University Medical Center (LUMC),Department of Ophthalmology
来源：
Eye | 2013年 / 27卷
关键词：
uveal melanoma; tumour immunology; macrophages; lymphocytes; cytokines; hypoxia;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Leukocytic infiltration is a common feature of human cancers, including those that develop in immunoprivileged sites, such as the eye. The infiltration of myeloid and T cells into tumours is part of the host response against cancer. In uveal melanoma, high densities of immune cells seem to be involved in tumour progression, as they are associated with the loss of one chromosome 3. The nature of this tumour microenvironment might offer therapeutic opportunities.
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收藏
页码：217 / 223
页数：6
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