Opioid overdose deaths can occur in patients with naltrexone implants

被引：30
|
作者：
Gibson, Amy E. [1 ]
Degenhardt, Louisa J.
Hall, Wayne D.
机构：
[1] Univ New S Wales, Natl Drug & Alcohol Res Ctr, Sydney, NSW, Australia
[2] Univ Queensland, Sch Populat Hlth, Brisbane, Qld, Australia
来源：
MEDICAL JOURNAL OF AUSTRALIA | 2007年 / 186卷 / 03期
关键词：
D O I：
10.5694/j.1326-5377.2007.tb00840.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
From Australian coronial records, we identified five deaths involving implantable naltrexone between 2000 and 2004. One man died from acute narcotism with a naltrexone implant in place and a blood naltrexone level of 0.3mg/L. A woman died of combined drug effect (including naltrexone) accompanied by severe pain from a naltrexone implant site. These cases indicate that patients can die from opioid overdose with a naltrexone implant and blood naltrexone levels higher than reported blockade levels.
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页码：152 / 153
页数：2
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