Theranostic Advances in Breast Cancer in Nuclear Medicine

被引:52
|
作者
Vahidfar, Nasim [1 ]
Aghanejad, Ayuob [2 ]
Ahmadzadehfar, Hojjat [3 ]
Farzanehfar, Saeed [1 ]
Eppard, Elisabeth [4 ,5 ]
机构
[1] Univ Tehran Med Sci, Vali Asr Hosp, Dept Nucl Med, Tehran 1419733141, Iran
[2] Tabriz Univ Med Sci, Biomed Inst, Res Ctr Pharmaceut Nanotechnol, Tabriz 51368, Iran
[3] Klinikum Westfalen, Dept Nucl Med, D-44149 Dortmund, Germany
[4] Positronpharma SA, Rancagua 878, Santiago 7500621, Chile
[5] Univ Hosp Magdeburg, Dept Nucl Med, Leipziger Str 44, D-39120 Magdedurg, Germany
关键词
theranostic; radiopharmaceutical; imaging; therapy; GASTRIN-RELEASING-PEPTIDE; NEUROENDOCRINE TUMORS; BOMBESIN RECEPTORS; PET; EXPRESSION; DIAGNOSIS; SUBTYPES; FIBROBLASTS; LIGANDS; PATIENT;
D O I
10.3390/ijms22094597
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The implication of 'theranostic' refers to targeting an identical receptor for diagnostic and therapeutic purposes, by the same radioligand, simultaneously or separately. In regard to extensive efforts, many considerable theranostic tracers have been developed in recent years. Emerging evidence strongly demonstrates the tendency of nuclear medicine towards therapies based on a diagnosis. This review is focused on the examples of targeted radiopharmaceuticals for the imaging and therapy of breast cancer.
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页数:17
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