Nanosecond time-gated spectroscopy of laser-ablation plume of human hair to detect calcium for potential diagnoses

被引：8

作者：

Ohmi, M

Nakamura, M

Morimoto, S

Haruna, M

机构：

[1] Osaka Univ, Fac Med, Sch Allied Hlth Sci, Suita, Osaka 5650871, Japan

[2] Osaka Univ, Grad Sch Med, Dept Geriatr Med, Suita, Osaka 5650871, Japan

来源：

OPTICAL REVIEW | 2000年 / 7卷 / 04期

关键词：

tissue laser ablation; plume luminescence; time-gated spectroscopy; calcium detection; optical diagnosis;

D O I：

10.1007/s10043-000-0353-x

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We demonstrate the nanosecond time-gated spectroscopy of plume luminescence in UV laser ablation of human hair. Clear and sharp peaks of calcium ion (Ca(+)) appear in the spectrum although the Ca content is only 0.1% in human hair. Highly sensitive detection of Ca is thus possible. In the experiment, the peak intensity of Ca(+) was measured for human hair samples of female subjects over a wide range of age, and compared to the bone mineral density of the lumbar vertebrae of the subjects themselves. Our experimental results suggest that this specific spectroscopy has the potential for novel diagnoses including monitoring of daily Ca intake and a screening diagnosis of osteoporosis. The spectroscopic system and time transition of plume-luminescence spectra are also described.

引用

页码：353 / 357

页数：5