Catalyst-free three-component reaction to synthesize chiral α-amino phosphine oxides

被引：13
|
作者：
Li, Xi-An [1 ]
Li, Jia-Yuan [1 ]
Yang, Bin [1 ]
Yang, Shang-Dong [1 ,2 ]
机构：
[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
[2] Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China
来源：
RSC ADVANCES | 2014年 / 4卷 / 75期
关键词：
KABACHNIK-FIELDS REACTION; METAL-FREE SYNTHESIS; AMINOPHOSPHONIC ACIDS; STEREOSELECTIVE-SYNTHESIS; BIOLOGICAL-ACTIVITY; C-C; FUNCTIONALIZATION; DERIVATIVES; INHIBITORS; MECHANISM;
D O I：
10.1039/c4ra05645k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A three-component reaction for high diastereoselective synthesis of chiral alpha-amino phosphine oxides has been developed and displayed environmentally friendly and atom efficient characteristics. The reaction proceeds smoothly without catalysts or additives.
引用
收藏
页码：39920 / 39923
页数：4
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