Efficient deprotection of F-BODIPY derivatives: removal of BF2 using Bronsted acids

被引：29

作者：

Yu, Mingfeng ^{[1
]}

Wong, Joseph K. -H. ^{[1
]}

Tang, Cyril ^{[1
]}

Turner, Peter ^{[2
]}

Todd, Matthew H. ^{[1
]}

Rutledge, Peter J. ^{[1
]}

机构：

[1] Univ Sydney, Sch Chem, Sydney, NSW 2006, Australia

[2] Univ Sydney, Sch Chem, Crystal Struct Anal Facil, Sydney, NSW 2006, Australia

来源：

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 11卷

基金：

澳大利亚研究理事会;

关键词：

Bronsted acids; click chemistry; deboration; dipyrrins; F-BODIPYs; PHOTOPHYSICAL PROPERTIES; SPECTRAL PROPERTIES; BORON; DIPYRRINS; STRATEGY; COMPLEX; DESIGN;

D O I：

10.3762/bjoc.11.6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The effective and efficient removal of the BF2 moiety from F-BODIPY derivatives has been achieved using two common Bronsted acids; treatment with trifluoroacetic acid (TFA) or methanolic hydrogen chloride (HCl) followed by work-up with Ambersep(R) 900 resin (hydroxide form) effects this conversion in near-quantitative yields. Compared to existing methods, these conditions are relatively mild and operationally simple, requiring only reaction at room temperature for six hours (TFA) or overnight (HCl).

引用

页码：1 / 5

页数：5

共 16 条

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