Soluble guanylyl cyclase (sGC) stimulators and activators decrease blood pressure and proteinuria in a rat model of preeclampsia

被引:0
|
作者
Robinson, Ta'Shariah [1 ]
Gillis, Ellen E. [1 ]
Garrett, Michael R. [1 ]
George, Eric [2 ]
Granger, Joey P. [2 ]
Sasser, Jennifer M. [1 ]
机构
[1] Univ Mississippi, Med Ctr, Pharmacol, Jackson, MS 39216 USA
[2] Univ Mississippi, Med Ctr, Physiol, Jackson, MS 39216 USA
来源
FASEB JOURNAL | 2016年 / 30卷
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
1212.5
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Soluble guanylyl cyclase stimulators and activators: Promising drugs for the treatment of hypertension?
    Gawrys, Olga
    Kala, Petr
    Sadowski, Janusz
    Melenovsky, Vojtech
    Sandner, Peter
    Cervenka, Ludek
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2025, 987
  • [2] Soluble Guanylyl Cyclase Stimulators And Activators Inhibit Hypoxia-induced Placental Sflt-1 Levels
    Patel, Bijalben
    Bakrania, Bhavisha
    Granger, Joey
    HYPERTENSION, 2019, 74
  • [3] DIFFERENTIAL INVOLVEMENT OF β1 REGULATORY DOMAIN AMINO ACID RESIDUES IN THE ACTIVATION OF SOLUBLE GUANYLYL CYCLASE (SGC) BY NITRIC OXIDE AND SGC ACTIVATORS
    Zhou, Z.
    Marazioti, A.
    Giannis, A.
    Spyroulias, G.
    Papapetropoulos, A.
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2014, 115 : 111 - 111
  • [4] Aging and chronic hypertension decrease expression of rat aortic soluble guanylyl cyclase
    Klöss, S
    Bouloumié, A
    Mülsch, A
    HYPERTENSION, 2000, 35 (01) : 43 - 47
  • [5] Genetic mapping of soluble guanylyl cyclase genes - Implications for linkage to blood pressure in the Dahl rat
    Azam, M
    Gupta, G
    Chen, W
    Wellington, S
    Warburton, D
    Danziger, RS
    HYPERTENSION, 1998, 32 (01) : 149 - 154
  • [6] Novel Therapies in Heart Failure with Reduced Ejection Fraction: from Soluble Guanylyl Cyclase Stimulators to Cardiac Myosin Activators
    Papadimitriou, Lampros
    Hernandez, Gabriel A.
    Lennep, Brandon
    Long, Robert C.
    Butler, Javed
    Kalogeropoulos, Andreas P.
    CURRENT TREATMENT OPTIONS IN CARDIOVASCULAR MEDICINE, 2021, 23 (05)
  • [7] Novel Therapies in Heart Failure with Reduced Ejection Fraction: from Soluble Guanylyl Cyclase Stimulators to Cardiac Myosin Activators
    Lampros Papadimitriou
    Gabriel A. Hernandez
    Brandon Lennep
    Robert C. Long
    Javed Butler
    Andreas P. Kalogeropoulos
    Current Treatment Options in Cardiovascular Medicine, 2021, 23 (5)
  • [8] Blood pressure in mice with a targeted deletion of the soluble guanylyl cyclase alpha 1 subunit
    Brouckaert, P
    Buys, E
    Sips, P
    Rogge, E
    Dewerchin, M
    Cauwels, A
    JOURNAL OF VASCULAR RESEARCH, 2005, 42 : 10 - 10
  • [9] Novel soluble guanylyl cyclase activators increase glomerular cGMP, induce vasodilation and improve blood flow in the murine kidney
    Stehle, Daniel
    Xu, Min Ze
    Schomber, Tibor
    Hahn, Michael G.
    Schweda, Frank
    Feil, Susanne
    Kraehling, Jan R.
    Eitner, Frank
    Patzak, Andreas
    Sandner, Peter
    Feil, Robert
    Benardeau, Agnes
    BRITISH JOURNAL OF PHARMACOLOGY, 2022, 179 (11) : 2476 - 2489
  • [10] New potential soluble guanylyl cyclase (sGC) activators: Design, synthesis and NMR-driven interaction studies with the Nostoc sp. HNOX domain
    Roumana, Aggeliki
    Argyriou, Aikaterini I.
    Makrynitsa, Garyfallia I.
    Chasapi, Styliani A.
    Matsoukas, Minos-Timotheos
    Topouzis, Stavros
    JOURNAL OF TRANSLATIONAL MEDICINE, 2019, 17 (01)