Stress-induced obesity and the emotional nervous system

被引:526
|
作者
Dallman, Mary F. [1 ]
机构
[1] Univ Calif San Francisco, Dept Physiol, San Francisco, CA 94143 USA
来源
关键词
FOOD-INTAKE; ENERGY-BALANCE; WEIGHT CHANGE; GLUCOCORTICOID-RECEPTOR; EATING-DISORDERS; DAILY HASSLES; LARD INTAKE; HPA AXIS; BRAIN; INSULIN;
D O I
10.1016/j.tem.2009.10.004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Stress and emotional brain networks foster eating behaviors that can lead to obesity. The neural networks underlying the complex interactions among stressors, body, brain and food intake are now better understood. Stressors, by activating a neural stress-response network, bias cognition toward increased emotional activity and degraded executive function. This causes formed habits to be used rather than a cognitive appraisal of responses. Stress also induces secretion of glucocorticoids, which increases motivation for food, and insulin, which promotes food intake and obesity. Pleasurable feeding then reduces activity in the stress-response network, reinforcing the feeding habit. These effects of stressors emphasize the importance of teaching mental reappraisal techniques to restore responses from habitual to thoughtful, thus battling stress-induced obesity.
引用
收藏
页码:159 / 165
页数:7
相关论文
共 50 条
  • [1] Functions of Stress-Induced Lipid Droplets in the Nervous System
    Islimye, Eva
    Girard, Victor
    Gould, Alex P.
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 10
  • [2] STRESS-INDUCED ACTIVATION OF THE SYMPATHETIC NERVOUS-SYSTEM
    GOLDSTEIN, DS
    BAILLIERES CLINICAL ENDOCRINOLOGY AND METABOLISM, 1987, 1 (02): : 253 - 278
  • [3] A role for CRH and the sympathetic nervous system in stress-induced immunosuppression
    Friedman, EM
    Irwin, MR
    STRESS: BASIC MECHANISMS AND CLINICAL IMPLICATIONS, 1995, 771 : 396 - 418
  • [4] STRESS-INDUCED IMMUNE SUPPRESSION - ROLE OF THE AUTONOMIC NERVOUS-SYSTEM
    IRWIN, M
    CORTICOTROPIN-RELEASING FACTOR AND CYTOKINES: ROLE IN THE STRESS RESPONSE: HANS SELYE SYMPOSIUM ON NEUROENDOCRINOLOGY AND STRESS, 1993, 697 : 203 - 218
  • [5] Stress-induced Reactivity of the Sympathetic Nervous System in Physicians with occupational Burnout
    von Kaenel, R.
    Princip, M.
    Holzgang, S. A.
    Sivakumar, S.
    Pazhenkottil, A. P.
    Vieito, D. Gomez
    Zuccarella-Hackl, C.
    ZEITSCHRIFT FUR PSYCHOSOMATISCHE MEDIZIN UND PSYCHOTHERAPIE, 2024, 70 (02): : 164 - 165
  • [6] Brains and brawn: Stress-induced myokine abates nervous system aging
    Tsui, Kimberly
    Dishart, Julian G.
    Dillin, Andrew
    CELL METABOLISM, 2021, 33 (06) : 1067 - 1069
  • [7] The role of the sympathetic nervous system in emotional stress induced humoral immunosuppression
    Lin, WJ
    Wang, WW
    Xu, L
    Zhao, Z
    AUSTRALIAN JOURNAL OF PSYCHOLOGY, 2005, 57 : 224 - 225
  • [8] The natriuretic peptide system as a possible therapeutic target for stress-induced obesity
    Mutschler, Jochen
    Kiefer, Falk
    MEDICAL HYPOTHESES, 2011, 76 (03) : 388 - 390
  • [9] Stress-induced and emotional eating in animals: A review of the experimental evidence and implications for companion animal obesity
    McMillan, Franklin D.
    JOURNAL OF VETERINARY BEHAVIOR-CLINICAL APPLICATIONS AND RESEARCH, 2013, 8 (05) : 376 - 385
  • [10] Pregabalin prevents repetitive stress-induced dysfunctions in the central nervous system of mice
    Kikuchi, Akinori
    Iwai, Takashi
    Watanabe, Shun
    Ikeda-Matsuo, Yuri
    Naito, Yasuhito
    Tanabe, Mitsuo
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2015, 128 (03) : S165 - S165