Molar-scale synthesis of 1,2:5,6-Di-O-isopropylidene-α-D-allofuranose:: DMSO oxidation of 1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose and subsequent sodium borohydride reduction

被引：16
|
作者：
Christensen, SM [1 ]
Hansen, HF [1 ]
Koch, T [1 ]
机构：
[1] Santaris Pharma AS, DK-2970 Horsholm, Denmark
来源：
ORGANIC PROCESS RESEARCH & DEVELOPMENT | 2004年 / 8卷 / 05期
关键词：
D O I：
10.1021/op049903t
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Two variants of oxidation with DMSO followed by sodium borohydride reduction have been investigated to make the synthesis of 1,2:5,6-di-O-isopropylidene-alpha-D-allofuranose (4) suitable for large-scale manufacturing.
引用
收藏
页码：777 / 780
页数：4
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