Endocrine-Disrupting Chemicals Role in Drug Abuser: A Review Study

被引：0

作者：

Wiraagni, Idha Arfianti ^{[1
,2
]}

Mohd, Mustafa Ali ^{[3
]}

Rashid, Rusdi Abdul ^{[4
]}

Haron, Didi Erwandi Bin Mohamad ^{[3
]}

机构：

[1] Univ Malaya, Fac Med, Dept Pathol, Kuala Lumpur, Malaysia

[2] Univ Gadjah Mada, Fac Med, Dept Forens Med & Medicolegal, Yogyakarta, Indonesia

[3] Univ Malaya, Fac Med, Shimadzu UM Ctr Xenobiot Studies SUCXeS, Kuala Lumpur, Malaysia

[4] Univ Malaya, Fac Med, Dept Psychol Med, Kuala Lumpur, Malaysia

来源：

INTERNATIONAL JOURNAL OF MEDICAL TOXICOLOGY AND FORENSIC MEDICINE | 2020年 / 10卷 / 04期

关键词：

EDCs; Bisphenol; Paraben; BISPHENOL-A CONCENTRATIONS; HUMAN EXPOSURE; PARABENS; URINE; BLOOD; DERIVATIVES; BIOMARKERS; TRICLOSAN; ANALOGS; BPA;

D O I：

10.32598/ijmtfm.v10i4.26324

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

Endocrine-disrupting Chemicals (EDCs) are exogenous chemicals that influence many aspects of natural hormone actions. Bisphenol is used in the industry, for increasing the thickness and durability of materials in certain plastics and resins. Paraben is used as preservatives in many pharmaceuticals, cosmetics, and some food products. EDCs can increase estrogen levels inside the body, and estrogen itself can increase the monoamine effect (dopamine, serotonin), neuronal excitability, neuropeptide transmitter mechanism, and drug metabolism. In drug abusers, this effect can develop greater craving behavior, addiction, and relapse.

引用

页数：8

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