Synergistic effect of quinacrine in combination with decitabine for the treatment of acute myeloid leukemia cells in vitro: implication for treatment of AML in the elderly

被引:0
|
作者
Wang, Wenge [1 ]
Dicker, David T. [2 ,3 ]
Claxton, David F. [1 ]
Wang, Hong-Gang [4 ]
El-Deiry, Wafik S. [2 ,3 ]
机构
[1] Penn State Hershey Med Ctr, Inst Canc, Hematol Oncol, Hershey, PA USA
[2] Fox Chase Canc Ctr, Dept Med Oncol, Philadelphia, PA 19111 USA
[3] Fox Chase Canc Ctr, Mol Therapeut Program, Philadelphia, PA 19111 USA
[4] Penn State Coll Medicne, Dept Pediat, Hershey, PA USA
关键词
D O I
10.1158/1538-7445.AM2015-3486
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
3486
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Decitabine in Combination with Venetoclax in Six Elderly Patients with Acute Myeloid Leukemia (AML)
    Rios, Adan
    Kanaan, Zeyad
    Nghia Nguyen
    Rekoff, Gregg
    Chen, Lei
    Wahed, Amer
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2018, 18 : S211 - S211
  • [2] Decitabine in the treatment of acute myeloid leukemia in elderly patients
    Malik, Priya
    Cashen, Amanda F.
    CANCER MANAGEMENT AND RESEARCH, 2014, 6 : 53 - 61
  • [3] Decitabine for the treatment of acute myeloid leukemia
    Bryan, Jeffrey
    Kantarjian, Hagop
    Jabbour, Elias
    EXPERT OPINION ON ORPHAN DRUGS, 2013, 1 (08): : 661 - 673
  • [4] Durable response with venetoclax in combination with decitabine or azacitadine in elderly patients with acute myeloid leukemia (AML).
    Dinardo, Courtney Denton
    Pratz, Keith William
    Potluri, Jalaja
    Pullarkat, Vinod A.
    Jonas, Brian Andrew
    Wei, Andrew H.
    Becker, Pamela Sue
    Frankfurt, Olga
    Xu, Tu
    Hong, Wan-Jen
    Chyla, Brenda
    Pollyea, Daniel Aaron
    Letai, Anthony G.
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
  • [5] Durable Response with Venetoclax in Combination with Decitabine or Azacitidine in Elderly Patients with Acute Myeloid Leukemia (AML)
    DiNardo, Courtney D.
    Pratz, Keith
    Potluri, Jalaja
    Pullarkat, Vinod
    Jonas, Brian A.
    Wei, Andrew H.
    Becker, Pamela S.
    Frankfurt, Olga
    Xu, Tu
    Hong, Wan-Jen
    Chyla, Brenda
    Pollyea, Daniel A.
    Letai, Anthony
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2018, 18 : S201 - S201
  • [6] Treatment of elderly acute myeloid leukemia (AML) patients with the combination of mitoxantrone and cytarabine (MAC).
    Marinakis, T
    Galanopoulos, AG
    Zomas, A
    Michalis, E
    Gortzolidis, G
    Tsakiridou, A
    Xanthopoulos, V
    Theodoropoulos, G
    Goumakou, H
    Georgiakaki, M
    Grigoraki, V
    Anagnostopoulos, NI
    BLOOD, 2005, 106 (11) : 235B - 235B
  • [7] Emerging treatment strategies for acute myeloid leukemia (AML) in the elderly
    Kuendgen, Andrea
    Germing, Ulrich
    CANCER TREATMENT REVIEWS, 2009, 35 (02) : 97 - 120
  • [8] Repositioning of Quinacrine for Treatment of Acute Myeloid Leukemia
    Eriksson, Anna
    Osterros, Albin
    Hassan, Sadia
    Gullbo, Joachim
    Rickardson, Linda
    Jarvius, Malin
    Nygren, Peter
    Fryknas, Marten
    Hoglund, Martin
    Larsson, Rolf
    BLOOD, 2014, 124 (21)
  • [9] SAFETY AND EFFICACY OF VENETOCLAX (VEN) IN COMBINATION WITH DECITABINE OR AZACITIDINE IN TREATMENT-NAIVE, ELDERLY PATIENTS (≥65 YEARS) WITH ACUTE MYELOID LEUKEMIA (AML)
    Pratz, K.
    Pollyea, D. A.
    Jonas, B. A.
    Pullarkat, V.
    Wei, A.
    Arellano, M.
    Becker, P. S.
    Frankfurt, O.
    Thirman, M.
    Pigneux, A.
    Recher, C.
    Seymour, J. F.
    Dvorak, N.
    Xu, T.
    Humerickhouse, R.
    Mabry, M.
    Potluri, J.
    Letai, A.
    DiNardo, C.
    HAEMATOLOGICA, 2017, 102 : 175 - 176
  • [10] Safety and Efficacy of Venetoclax (VEN) in Combination With Decitabine or Azacitidine in Treatment-Naive, Elderly Patients (≥65 Years) With Acute Myeloid Leukemia (AML)
    Pratz, K.
    Pollyea, D.
    Jonas, B.
    Pullarkat, V.
    Wei, A.
    Arellano, M.
    Becker, P.
    Frankfurt, O.
    Thirman, M.
    Pigneux, A.
    Recher, C.
    Seymour, J.
    Dvorak, N.
    Xu, T.
    Humerickhouse, R.
    Mabry, M.
    Potluri, J.
    Letai, A.
    DiNardo, C.
    BRITISH JOURNAL OF HAEMATOLOGY, 2018, 181 : 11 - 12