Rh-Catalyzed C-C/C-N bond formation via C-H activation: synthesis of 2H-indazol-2-yl-benzo[a]carbazoles

被引：21
|
作者：
Kumar, Sundaravel Vivek [1 ]
Banerjee, Sonbidya [1 ]
Punniyamurthy, Tharmalingam [1 ]
机构：
[1] Indian Inst Technol Guwahati, Dept Chem, Gauhati 781039, India
来源：
ORGANIC CHEMISTRY FRONTIERS | 2019年 / 6卷 / 23期
关键词：
BIOLOGICAL EVALUATION; FUNCTIONALIZATIONS; C7-ARYLATION; COMBINATION; CHEMISTRY; DISCOVERY; ARENES;
D O I：
10.1039/c9qo01120j
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Rh-Catalyzed tandem site-selective C-H activation and ring opening/cyclization of 7-azabenzonorbornadienes with aryl-2H-indazoles is developed to furnish indazolyl-benzocarbazoles. The mechanistic studies suggest that the second C-H activation is the product-determining step. The use of an air stable cationic Rh-catalyst and site-selectivity, and substrate scope are the important practical features.
引用
收藏
页码：3885 / 3890
页数：6
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