Pan-Cancer Bioinformatics Analysis of Gene UBE2C

被引：12
|
作者：
Yuan, Lin [1 ]
Yang, Zhenyu [1 ]
Zhao, Jing [1 ]
Sun, Tao [1 ]
Hu, Chunyu [1 ]
Shen, Zhen [2 ]
Yu, Guanying [3 ]
机构：
[1] Qilu Univ Technol, Shandong Acad Sci, Sch Comp Sci & Technol, Jinan, Peoples R China
[2] Nanyang Inst Technol, Sch Comp & Software, Nanyang, Peoples R China
[3] Shandong First Med Univ, Dept Gastrointestinal Surg, Cent Hosp, Jinan, Peoples R China
来源：
FRONTIERS IN GENETICS | 2022年 / 13卷
基金：
中国国家自然科学基金;
关键词：
gene Expression; pan-cancer; GSE data; prognostic analysis; TCGA; immune infiltration; NETWORK;
D O I：
10.3389/fgene.2022.893358
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a gene that encodes protein. Disorders associated with UBE2C include methotrexate-related lymphatic hyperplasia and complement component 7 deficiency. The encoded protein is necessary for the destruction of mitotic cell cyclins and cell cycle progression, and may be involved in cancer progression. In this paper, on the basis of public databases, we study the expression differential mechanism of gene expression of UBE2C in various tumors and the performance of prognosis, clinical features, immunity, methylation, etc.
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页数：11
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