Enantioselectivity of Candida antarctica lipase for some synthetic substrates including aliphatic secondary alcohols

被引：57
|
作者：
Ohtani, T
Nakatsukasa, H
Kamezawa, M
Tachibana, H
Naoshima, Y
机构：
[1] Okayama Univ Sci, Fac Informat, Okayama 700, Japan
[2] Konan Chem Ind Co Ltd, Takatsuki, Osaka 569, Japan
来源：
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC | 1998年 / 4卷 / 1-2期
关键词：
lipases; Candida antarctica; enantioselectivity; hydrolysis; esterification; secondary alcohols;
D O I：
10.1016/S1381-1177(97)00021-0
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Candida antarctica lipase (Novozym 435) showed good to high enantioselectivity in the acylation of aliphatic and aromatic secondary alcohols (E = 38-166), and higher enantioselectivity in the hydrolysis of their corresponding acetates than other lipases tested, including lipases AY and MY (Candida sp.) and lipases PS, AK and LIP (Pseudomonas sp.). (C) 1998 Elsevier Science B.V.
引用
收藏
页码：53 / 60
页数：8
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