THE COMBINATION OF VENETOCLAX AND FTY720 HAS A SYNERGISTIC PRO-APOPTOTIC EFFECT IN ACUTE MYELOID LEUKEMIA

被引：0
|
作者：
Irene, Peris [1 ]
Elena, Martinez-Balsalobre [2 ]
Elena, Arriazu [3 ]
Silvia, Romero-Murillo [1 ]
Javier, Marco [1 ]
Nerea, Marcotegui [4 ]
Andrea, Torres-Lopez [5 ]
Carmen, Mateos M. [5 ]
Luisa, Cayuela M. [2 ]
Dolores, Odero M. [1 ]
Carmen, Vicente [1 ]
机构：
[1] Univ Navarra, Pamplona, Spain
[2] Inst Murciano Invest Biosanitaria, Murcia, Spain
[3] Inst Salud Carlos III, Madrid, Spain
[4] CIMA Univ Navarra, Pamplona, Spain
[5] Complejo Hosp Navarra, Pamplona, Spain
来源：
HAEMATOLOGICA | 2020年 / 105卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
CO-071
引用
收藏
页码：53 / 54
页数：2
相关论文
共 50 条
  • [1] Hymeglusin Enhances the Pro-Apoptotic Effects of Venetoclax in Acute Myeloid Leukemia
    Zhou, Cheng
    Wang, Zhiqin
    Yang, Shuanghui
    Li, Huan
    Zhao, Liang
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [2] Oridonin Synergistically Enhances the Pro-Apoptotic Effect of Venetoclax on Acute Myeloid Leukemia Cells by Inhibiting AKT Signaling
    Chen, Lin
    Li, Dongbei
    Guo, Xiaoli
    Cheng, Cheng
    Wei, Xudong
    FRONTIERS IN BIOSCIENCE-LANDMARK, 2023, 28 (09):
  • [3] Lipid Nanosystems Enhance the Bioavailability and the Therapeutic Efficacy of FTY720 in Acute Myeloid Leukemia
    de Mendoza, A. Estella-Hermoso
    Castello-Cros, R.
    Imbuluzqueta, E.
    Cirauqui, C.
    Pippa, R.
    Odero, M. D.
    Blanco-Prieto, M. J.
    JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 2015, 11 (04) : 691 - 701
  • [4] FTY720 induces non-canonical phosphatidylserine externalization and cell death in acute myeloid leukemia
    Young, Megan M.
    Van Bui
    Chen, Chong
    Wang, Hong-Gang
    CELL DEATH & DISEASE, 2019, 10 (11)
  • [5] FTY720 induces non-canonical phosphatidylserine externalization and cell death in acute myeloid leukemia
    Megan M. Young
    Van Bui
    Chong Chen
    Hong-Gang Wang
    Cell Death & Disease, 10
  • [6] Combination effect of tacrolimus and FTY720 in liver transplantation in rats
    Tamura, A
    Li, XK
    Funeshima, N
    Enosawa, S
    Amemiya, H
    Suzuki, S
    TRANSPLANTATION PROCEEDINGS, 1999, 31 (07) : 2785 - 2786
  • [7] The immunomodulator FTY720 has a direct cytoprotective effect in oligodendrocyte progenitors
    Coelho, Rochelle P.
    Payne, Shawn G.
    Bittman, Robert
    Spiegel, Sarah
    Sato-Bigbee, Carmen
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2007, 323 (02): : 626 - 635
  • [8] FTY720, a novel immunosuppressant, shows a synergistic effect in combination with FK 506 in rat allograft models
    Hoshino, Y
    Yanagawa, Y
    Ohtsuki, M
    Nakayama, S
    Hashimoto, T
    Chiba, K
    TRANSPLANTATION PROCEEDINGS, 1999, 31 (1-2) : 1224 - 1226
  • [9] Rescue effect of FTY720 on acute renal rejection in dogs
    Yuzawa, K
    Otsuka, M
    Taniguchi, H
    Takada, Y
    Sakurayama, N
    Jinzenji, Y
    Suzuki, S
    Fukao, K
    TRANSPLANTATION PROCEEDINGS, 1999, 31 (1-2) : 872 - 872
  • [10] The Anti-Proliferative and Pro-apoptotic Effect of Topotecan in Combination With Thymoquinone in Acute Myelogenous Leukemia
    Rizk, Sandra
    Khalife, Rana
    Tarras, Omayr
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2014, 14 : S125 - S126
12345