Exome sequencing of Finnish isolates enhances rare-variant association power (vol 572, pg 323, 2019)

被引：3

作者：

Locke, Adam E.

Steinberg, Karyn Meltz

Chiang, Charleston W. K.

Service, Susan K.

Havulinna, Aki S.

Stell, Laurel

Pirinen, Matti

Abel, Haley J.

Chiang, Colby C.

Fulton, Robert S.

Jackson, Anne U.

Kang, Chul Joo

Kanchi, Krishna L.

Koboldt, Daniel C.

Larson, David E.

Nelson, Joanne

Nicholas, Thomas J.

Pietila, Arto

Ramensky, Vasily

Ray, Debashree

Scott, Laura J.

Stringham, Heather M.

Vangipurapu, Jagadish

Welch, Ryan

Yajnik, Pranav

Yin, Xianyong

Eriksson, Johan G.

Ala-Korpela, Mika

Jarvelin, Marjo-Riitta

Mannikko, Minna

Laivuori, Hannele

Project, FinnGen

Dutcher, Susan K.

Stitziel, Nathan O.

Wilson, Richard K.

Hall, Ira M.

Sabatti, Chiara

Palotie, Aarno

Salomaa, Veikko

Laakso, Markku

Ripatti, Samuli

Boehnke, Michael

Freimer, Nelson B.

机构：

[1] Washington University School of Medicine,Department of Medicine

[2] Washington University School of Medicine,McDonnell Genome Institute

[3] University of Michigan School of Public Health,Department of Biostatistics and Center for Statistical Genetics

[4] Washington University School of Medicine,Department of Pediatrics

[5] University of California Los Angeles,Center for Neurobehavioral Genetics, Jane and Terry Semel Institute for Neuroscience and Human Behavior

[6] University of Southern California,Center for Genetic Epidemiology, Department of Preventive Medicine, Keck School of Medicine

[7] University of Southern California,Quantitative and Computational Biology Section, Department of Biological Sciences

[8] University of Helsinki,Institute for Molecular Medicine Finland (FIMM)

[9] National Institute for Health and Welfare,Department of Biomedical Data Science

[10] Stanford University,Department of Public Health

[11] University of Helsinki,Helsinki Institute for Information Technology HIIT and Department of Mathematics and Statistics

[12] University of Helsinki,Department of Genetics

[13] Washington University School of Medicine,The Institute for Genomic Medicine

[14] Nationwide Children’s Hospital,Department of Pediatrics

[15] The Ohio State University College of Medicine,USTAR Center for Genetic Discovery and Department of Human Genetics

[16] University of Utah,Departments of Epidemiology and Biostatistics, Bloomberg School of Public Health

[17] Federal State Institution “National Medical Research Center for Preventive Medicine” of the Ministry of Healthcare of the Russian Federation,Institute of Clinical Medicine, Internal Medicine

[18] Johns Hopkins University,Department of Public Health Solutions

[19] University of Eastern Finland,Department of General Practice and Primary Health Care, University of Helsinki

[20] National Institute for Health and Welfare,Systems Epidemiology

[21] Folkhälsan Research Center,Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu

[22] Helsinki and Helsinki University Hospital,NMR Metabolomics Laboratory, School of Pharmacy

[23] Baker Heart and Diabetes Institute,Population Health Science, Bristol Medical School

[24] University of Oulu,Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences

[25] University of Eastern Finland,Biocenter Oulu

[26] University of Bristol,Center for Life Course Health Research, Faculty of Medicine

[27] Medical Research Council Integrative Epidemiology Unit at the University of Bristol,Unit of Primary Health Care

[28] The Alfred Hospital,Department of Epidemiology and Biostatistics, MRC

[29] Monash University,PHE Centre for Environment and Health, School of Public Health

[30] University of Oulu,Department of Life Sciences, College of Health and Life Sciences

[31] University of Oulu,Northern Finland Birth Cohorts, Faculty of Medicine

[32] Oulu University Hospital,Medical and Clinical Genetics

[33] Imperial College London,Department of Obstetrics and Gynecology, Tampere University Hospital and University of Tampere

[34] Brunel University London,Cardiovascular Division, Department of Medicine

[35] University of Oulu,Department of Statistics

[36] University of Helsinki and Helsinki University Hospital,Analytical and Translational Genetics Unit (ATGU), Psychiatric & Neurodevelopmental Genetics Unit, Departments of Psychiatry and Neurology

[37] Faculty of Medicine and Health Technology,Department of Medicine

[38] Washington University School of Medicine,undefined

[39] Stanford University,undefined

[40] Massachusetts General Hospital,undefined

[41] Broad Institute of MIT and Harvard,undefined

[42] Kuopio University Hospital,undefined

来源：

NATURE | 2019年 / 575卷 / 7783期

关键词：

D O I：

10.1038/s41586-019-1726-x

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

An Amendment to this paper has been published and can be accessed via a link at the top of the paper.

引用

页码：E4 / E4

页数：1

共 6 条

[1] Exome sequencing of Finnish isolates enhances rare-variant association power
Locke, Adam E.
Steinberg, Karyn Meltz
Chiang, Charleston W. K.
Service, Susan K.
Havulinna, Aki S.
Stell, Laurel
Pirinen, Matti
Abel, Haley J.
Chiang, Colby C.
Fulton, Robert S.
Jackson, Anne U.
Kang, Chul Joo
Kanchi, Krishna L.
Koboldt, Daniel C.
Larson, David E.
Nelson, Joanne
Nicholas, Thomas J.
Pietila, Arto
Ramensky, Vasily
Ray, Debashree
Scott, Laura J.
Stringham, Heather M.
Vangipurapu, Jagadish
Welch, Ryan
Yajnik, Pranav
Yin, Xianyong
Eriksson, Johan G.
Ala-Korpela, Mika
Jarvelin, Marjo-Riitta
Mannikko, Minna
Laivuori, Hannele
Dutcher, Susan K.
Stitziel, Nathan O.
Wilson, Richard K.
Hall, Ira M.
Sabatti, Chiara
Palotie, Aarno
Salomaa, Veikko
Laakso, Markku
Ripatti, Samuli
Boehnke, Michael
Freimer, Nelson B.
NATURE, 2019, 572 (7769) : 323 - +
[2] Exome sequencing of Finnish isolates enhances rare-variant association power
Adam E. Locke
Karyn Meltz Steinberg
Charleston W. K. Chiang
Susan K. Service
Aki S. Havulinna
Laurel Stell
Matti Pirinen
Haley J. Abel
Colby C. Chiang
Robert S. Fulton
Anne U. Jackson
Chul Joo Kang
Krishna L. Kanchi
Daniel C. Koboldt
David E. Larson
Joanne Nelson
Thomas J. Nicholas
Arto Pietilä
Vasily Ramensky
Debashree Ray
Laura J. Scott
Heather M. Stringham
Jagadish Vangipurapu
Ryan Welch
Pranav Yajnik
Xianyong Yin
Johan G. Eriksson
Mika Ala-Korpela
Marjo-Riitta Järvelin
Minna Männikkö
Hannele Laivuori
Susan K. Dutcher
Nathan O. Stitziel
Richard K. Wilson
Ira M. Hall
Chiara Sabatti
Aarno Palotie
Veikko Salomaa
Markku Laakso
Samuli Ripatti
Michael Boehnke
Nelson B. Freimer
Nature, 2019, 572 : 323 - 328
[3] Author Correction: Exome sequencing of Finnish isolates enhances rare-variant association power
Adam E. Locke
Karyn Meltz Steinberg
Charleston W. K. Chiang
Susan K. Service
Aki S. Havulinna
Laurel Stell
Matti Pirinen
Haley J. Abel
Colby C. Chiang
Robert S. Fulton
Anne U. Jackson
Chul Joo Kang
Krishna L. Kanchi
Daniel C. Koboldt
David E. Larson
Joanne Nelson
Thomas J. Nicholas
Arto Pietilä
Vasily Ramensky
Debashree Ray
Laura J. Scott
Heather M. Stringham
Jagadish Vangipurapu
Ryan Welch
Pranav Yajnik
Xianyong Yin
Johan G. Eriksson
Mika Ala-Korpela
Marjo-Riitta Järvelin
Minna Männikkö
Hannele Laivuori
Susan K. Dutcher
Nathan O. Stitziel
Richard K. Wilson
Ira M. Hall
Chiara Sabatti
Aarno Palotie
Veikko Salomaa
Markku Laakso
Samuli Ripatti
Michael Boehnke
Nelson B. Freimer
Nature, 2019, 575 : E4 - E4
[4] A W-test collapsing method for rare-variant association testing in exome sequencing data
Sun, Rui
Weng, Haoyi
Hu, Inchi
Guo, Junfeng
Wu, William K. K.
Zee, Benny Chung-Ying
Wang, Maggie Haitian
GENETIC EPIDEMIOLOGY, 2016, 40 (07) : 591 - 596
[5] Optimal Unified Approach for Rare-Variant Association Testing with Application to Small-Sample Case-Control Whole-Exome Sequencing Studies
Lee, Seunggeun
Emond, Mary J.
Bamshad, Michael J.
Barnes, Kathleen C.
Rieder, Mark J.
Nickerson, Deborah A.
Christiani, David C.
Wurfel, Mark M.
Lin, Xihong
AMERICAN JOURNAL OF HUMAN GENETICS, 2012, 91 (02) : 224 - 237
[6] Exome-sequencing in a large population-based study reveals a rare Asn396Ser variant in the LIPG gene associated with depressive symptoms (vol 22, pg 537, 2017)
Amin, N.
Jovanova, O.
Adams, H. H. H.
Dehghan, A.
Kavousi, M.
Vernooij, M. W.
Peeters, R. P.
de Vrij, F. M. S.
van der Lee, S. J.
van Rooij, J. G. J.
Uitterlinden, A. G.
Niessen, W. J.
Franco, O. H.
Kushner, S. A.
Ikram, M. A.
Tiemeier, H.
van Duijn, C. M.
MOLECULAR PSYCHIATRY, 2017, 22 (04) : 634 - 634

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