DIABETES SGLT2 inhibitors and diabetic ketoacidosis - a growing concern

被引:18
|
作者
Umpierrez, Guillermo E. [1 ]
机构
[1] Emory Univ, Sch Med, Endocrinol Metab & Lipids, 69 Jesse Hill Jr Dr, Atlanta, GA 30303 USA
基金
美国国家卫生研究院;
关键词
COTRANSPORTER; 2; INHIBITOR; CANAGLIFLOZIN; OUTCOMES;
D O I
10.1038/nrendo.2017.77
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Diabetic ketoacidosis is a worrying complication associated with the use of sodium/glucose cotransporter 2 (SGLT2) inhibitors in patients with type 1 diabetes mellitus (T1DM) or T2DM. A recent analysis of data in the FDA Adverse Event Reporting System by Fadini and colleagues adds to this concern.
引用
收藏
页码:441 / 442
页数:2
相关论文
共 50 条
  • [1] SGLT2 inhibitors and diabetic ketoacidosis — a growing concern
    Guillermo E. Umpierrez
    Nature Reviews Endocrinology, 2017, 13 : 441 - 442
  • [2] Diabetic ketoacidosis with SGLT2 inhibitors
    Musso, Giovanni
    Saba, Francesca
    Cassader, Maurizio
    Gambino, Roberto
    BMJ-BRITISH MEDICAL JOURNAL, 2020, 371
  • [3] SGLT2 Inhibitors and Ketoacidosis: Cause for Concern?
    Abate, Nicola
    Chandalia, Manisha
    METABOLIC SYNDROME AND RELATED DISORDERS, 2016, 14 (01) : 1 - 2
  • [4] SGLT2 inhibitors and euglycemic diabetic ketoacidosis
    Yousaf, Zohaib
    Ata, Fateen
    Khan, Adeel Ahmad
    Razok, Almurtada
    Akram, Jaweria
    Ali, Elrazi Awadelkarim Hamid
    Abdalhadi, Ahmed
    Danjuma, Mohammed I.
    Al Mohanadi, Dabia Hamad S. H.
    EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2021, 77 (09) : 1431 - 1433
  • [5] SGLT2 inhibitors and euglycemic diabetic ketoacidosis
    Zohaib Yousaf
    Fateen Ata
    Adeel Ahmad Khan
    Almurtada Razok
    Jaweria Akram
    Elrazi Awadelkarim Hamid Ali
    Ahmed Abdalhadi
    Mohammed I. Danjuma
    Dabia Hamad S. H. Al Mohanadi
    European Journal of Clinical Pharmacology, 2021, 77 : 1431 - 1433
  • [6] SGLT2 inhibitors and the risk of diabetic ketoacidosis
    Redford, Christopher
    Doherty, Laura
    Smith, Jamie
    PRACTICAL DIABETES, 2015, 32 (07) : 263 - 264A
  • [9] SGLT2 inhibitors and ketoacidosis in inpatients with diabetes
    Maharajan, V.
    Cherian, T.
    Jones, R.
    Hards, K.
    Anguelova, L.
    Lumb, A.
    Rea, R.
    Owen, K.
    Tan, G.
    DIABETIC MEDICINE, 2022, 39
  • [10] SGLT2 inhibitors increase risk for diabetic ketoacidosis in type 2 diabetes
    Griffin, Tomas P.
    Dinneen, Sean F.
    ANNALS OF INTERNAL MEDICINE, 2020, 173 (08) : JC40 - JC40