A Need for Basic Research on Fluid-Based Early Detection Biomarkers

被引:35
|
作者
Martin, Katherine J. [3 ]
Fournier, Marcia V. [3 ]
Reddy, G. Prem Veer [2 ]
Pardee, Arthur B. [1 ]
机构
[1] Dana Farber Canc Inst, Boston, MA 02115 USA
[2] Henry Ford Hosp, Vattikuti Urol Inst, Detroit, MI 48202 USA
[3] Bioarray Therapeut Inc, Belmont, MA USA
关键词
CIRCULATING NUCLEIC-ACIDS; GENE-EXPRESSION; CANCER; BLOOD; MARKERS; CELLS;
D O I
10.1158/0008-5472.CAN-10-0987
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Cancer continues to be a major cause of mortality despite decades of effort and expense. The problem reviewed here is that before many cancers are discovered they have already progressed to become drug resistant or metastatic. Biomarkers found in blood or other body fluids could supplement current clinical indicators to permit earlier detection and thereby reduce cancer mortality. Cancer Res; 70(13); 5203-6. (C) 2010 AACR.
引用
收藏
页码:5203 / 5206
页数:4
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