共 50 条
- [1] RVX-297-a novel BD2 selective inhibitor of BET bromodomainsBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016, 477 (01) : 62 - 67Kharenko, Olesya A.论文数: 0 引用数: 0 h-index: 0机构: Zenith Epigenet, Suite 300,4820 Richard Rd SW, Calgary, AB T3E 6L1, Canada Zenith Epigenet, Suite 300,4820 Richard Rd SW, Calgary, AB T3E 6L1, CanadaGesner, Emily M.论文数: 0 引用数: 0 h-index: 0机构: Zenith Epigenet, Suite 300,4820 Richard Rd SW, Calgary, AB T3E 6L1, Canada Zenith Epigenet, Suite 300,4820 Richard Rd SW, Calgary, AB T3E 6L1, CanadaPatel, Reena G.论文数: 0 引用数: 0 h-index: 0机构: Zenith Epigenet, Suite 300,4820 Richard Rd SW, Calgary, AB T3E 6L1, Canada Zenith Epigenet, Suite 300,4820 Richard Rd SW, Calgary, AB T3E 6L1, CanadaNorek, Karen论文数: 0 引用数: 0 h-index: 0机构: Zenith Epigenet, Suite 300,4820 Richard Rd SW, Calgary, AB T3E 6L1, Canada Zenith Epigenet, Suite 300,4820 Richard Rd SW, Calgary, AB T3E 6L1, CanadaWhite, Andre论文数: 0 引用数: 0 h-index: 0机构: Xtal BioStruct Inc, 12 Michigan Dr, Natick, MA 01760 USA Zenith Epigenet, Suite 300,4820 Richard Rd SW, Calgary, AB T3E 6L1, CanadaFontano, Eric论文数: 0 引用数: 0 h-index: 0机构: Xtal BioStruct Inc, 12 Michigan Dr, Natick, MA 01760 USA Zenith Epigenet, Suite 300,4820 Richard Rd SW, Calgary, AB T3E 6L1, CanadaSuto, Robert K.论文数: 0 引用数: 0 h-index: 0机构: Xtal BioStruct Inc, 12 Michigan Dr, Natick, MA 01760 USA Zenith Epigenet, Suite 300,4820 Richard Rd SW, Calgary, AB T3E 6L1, CanadaYoung, Peter R.论文数: 0 引用数: 0 h-index: 0机构: Zenith Epigenet, Suite 300,4820 Richard Rd SW, Calgary, AB T3E 6L1, Canada Zenith Epigenet, Suite 300,4820 Richard Rd SW, Calgary, AB T3E 6L1, CanadaMcLure, Kevin G.论文数: 0 引用数: 0 h-index: 0机构: Zenith Epigenet, Suite 300,4820 Richard Rd SW, Calgary, AB T3E 6L1, Canada Zenith Epigenet, Suite 300,4820 Richard Rd SW, Calgary, AB T3E 6L1, CanadaHansen, Henrik C.论文数: 0 引用数: 0 h-index: 0机构: Zenith Epigenet, Suite 300,4820 Richard Rd SW, Calgary, AB T3E 6L1, Canada Zenith Epigenet, Suite 300,4820 Richard Rd SW, Calgary, AB T3E 6L1, Canada
- [2] Bromodomains: a new target class for drug developmentNATURE REVIEWS DRUG DISCOVERY, 2019, 18 (08) : 609 - 628Cochran, Andrea G.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Early Discovery Biochem, San Francisco, CA 94080 USA Genentech Inc, Dept Early Discovery Biochem, San Francisco, CA 94080 USAConery, Andrew R.论文数: 0 引用数: 0 h-index: 0机构: Constellat Pharmaceut, Cambridge, MA 02142 USA Genentech Inc, Dept Early Discovery Biochem, San Francisco, CA 94080 USASims, Robert J., III论文数: 0 引用数: 0 h-index: 0机构: Constellat Pharmaceut, Cambridge, MA 02142 USA Genentech Inc, Dept Early Discovery Biochem, San Francisco, CA 94080 USA
- [3] Discovery of Epigenetic Regulator I-BET762: Lead Optimization to Afford a Clinical Candidate Inhibitor of the BET BromodomainsJOURNAL OF MEDICINAL CHEMISTRY, 2013, 56 (19) : 7501 - 7515Mirguet, Olivier论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, France GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceGosmini, Romain论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, France GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceToum, Jerome论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, France GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceClement, Catherine A.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, France GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceBarnathan, Melanie论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, France GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceBrusq, Jean-Marie论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, France GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceMordaunt, Jacqueline E.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Mol Discovery Res, Screening & Compound Profiling, Med Res Ctr, Stevenage SG1 2NY, Herts, England GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceGrimes, Richard M.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Mol Discovery Res, Screening & Compound Profiling, Med Res Ctr, Stevenage SG1 2NY, Herts, England GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceCrowe, Miriam论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Mol Discovery Res, Screening & Compound Profiling, Med Res Ctr, Stevenage SG1 2NY, Herts, England GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FrancePineau, Olivier论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, France GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceAjakane, Myriam论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, France GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceDaugan, Alain论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, France GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceJeffrey, Phillip论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, EMU Discovery Performance Unit, Quantitat Pharmacol, Stevenage SG1 2NY, Herts, England GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceCutler, Leanne论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, EMU Discovery Performance Unit, Quantitat Pharmacol, Stevenage SG1 2NY, Herts, England GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceHaynes, Andrea C.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, EMU Discovery Performance Unit, Quantitat Pharmacol, Stevenage SG1 2NY, Herts, England GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceSmithers, Nicholas N.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Discovery Performance Unit, Epinova, Stevenage SG1 2NY, Herts, England GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceChung, Chun-wa论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Mol Discovery Res, Computat & Struct Chem, Med Res Ctr, Stevenage SG1 2NY, Herts, England GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceBamborough, Paul论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Mol Discovery Res, Computat & Struct Chem, Med Res Ctr, Stevenage SG1 2NY, Herts, England GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceUings, Iain J.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Discovery Performance Unit, Epinova, Stevenage SG1 2NY, Herts, England GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceLewis, Antonia论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Mol Discovery Res, Screening & Compound Profiling, Med Res Ctr, Stevenage SG1 2NY, Herts, England GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceWitherington, Jason论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Discovery Performance Unit, Epinova, Stevenage SG1 2NY, Herts, England GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceParr, Nigel论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Discovery Performance Unit, Epinova, Stevenage SG1 2NY, Herts, England GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FrancePrinjha, Rab K.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Discovery Performance Unit, Epinova, Stevenage SG1 2NY, Herts, England GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, FranceNicodeme, Edwige论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, France GlaxoSmithKline R&D, Ctr Rech Francois Hyafil, F-91140 Villebon Sur Yvette, France
- [4] Bromodomains: a new target class for drug developmentNature Reviews Drug Discovery, 2019, 18 : 609 - 628Andrea G. Cochran论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of Early Discovery BiochemistryAndrew R. Conery论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of Early Discovery BiochemistryRobert J. Sims论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of Early Discovery Biochemistry
- [5] GSK789: A Selective Inhibitor of the First Bromodomains (BD1) of the Bromo and Extra Terminal Domain (BET) ProteinsJOURNAL OF MEDICINAL CHEMISTRY, 2020, 63 (17) : 9045 - 9069Watson, Robert J.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandBamborough, Paul论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Mol Discovery Res, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandBarnett, Heather论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Flexible Discovery Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandChung, Chun-wa论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Mol Discovery Res, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandDavis, Rob论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandGordon, Laurie论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Mol Discovery Res, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandGrandi, Paola论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Mol Discovery Res, Stevenage SG1 2NY, Herts, England GlaxoSmithKline, Cellzome GmbH, Mol Discovery Res, D-69117 Heidelberg, Germany GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandPetretich, Massimo论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Mol Discovery Res, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandPhillipou, Alex论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Mol Discovery Res, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandPrinjha, Rab K.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandRioja, Inmaculada论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandSoden, Peter论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandWerner, Thilo论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Mol Discovery Res, Stevenage SG1 2NY, Herts, England GlaxoSmithKline, Cellzome GmbH, Mol Discovery Res, D-69117 Heidelberg, Germany GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandDemont, Emmanuel H.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England
- [6] PFI-1, a Highly Selective Protein Interaction Inhibitor, Targeting BET BromodomainsCANCER RESEARCH, 2013, 73 (11) : 3336 - 3346Picaud, Sarah论文数: 0 引用数: 0 h-index: 0机构: Univ Oxford, Struct Genom Consortium, Oxford OX3 7DQ, Oxon, England Univ Oxford, Struct Genom Consortium, Oxford OX3 7DQ, Oxon, EnglandDa Costa, David论文数: 0 引用数: 0 h-index: 0机构: Univ Birmingham, Sch Canc Sci, Birmingham B15 2TT, W Midlands, England Univ Oxford, Struct Genom Consortium, Oxford OX3 7DQ, Oxon, EnglandThanasopoulou, Angeliki论文数: 0 引用数: 0 h-index: 0机构: Univ Basel, Dept Biomed, Lab Childhood Leukemia, CH-4031 Basel, Switzerland Univ Basel, Childrens Hosp, CH-4031 Basel, Switzerland Univ Oxford, Struct Genom Consortium, Oxford OX3 7DQ, Oxon, England论文数: 引用数: h-index:机构:Fish, Paul V.论文数: 0 引用数: 0 h-index: 0机构: Pfizer Worldwide R&D, Pfizer Worldwide Med Chem, Sandwich, Kent, England Univ Oxford, Struct Genom Consortium, Oxford OX3 7DQ, Oxon, EnglandPhilpott, Martin论文数: 0 引用数: 0 h-index: 0机构: Univ Oxford, Struct Genom Consortium, Oxford OX3 7DQ, Oxon, England Univ Oxford, Struct Genom Consortium, Oxford OX3 7DQ, Oxon, England论文数: 引用数: h-index:机构:论文数: 引用数: h-index:机构:Bunnage, Mark E.论文数: 0 引用数: 0 h-index: 0机构: Pfizer Worldwide R&D, Pfizer Worldwide Med Chem, Sandwich, Kent, England Univ Oxford, Struct Genom Consortium, Oxford OX3 7DQ, Oxon, EnglandOwen, Dafydd R.论文数: 0 引用数: 0 h-index: 0机构: Pfizer Worldwide R&D, Pfizer Worldwide Med Chem, Sandwich, Kent, England Univ Oxford, Struct Genom Consortium, Oxford OX3 7DQ, Oxon, EnglandBradner, James E.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02115 USA Harvard Univ, Sch Med, Dept Med, Boston, MA USA Univ Oxford, Struct Genom Consortium, Oxford OX3 7DQ, Oxon, EnglandTaniere, Philippe论文数: 0 引用数: 0 h-index: 0机构: Queen Elizabeth Med Ctr, Dept Cellular Pathol, Birmingham, W Midlands, England Univ Oxford, Struct Genom Consortium, Oxford OX3 7DQ, Oxon, EnglandO'Sullivan, Brendan论文数: 0 引用数: 0 h-index: 0机构: Queen Elizabeth Med Ctr, Dept Cellular Pathol, Birmingham, W Midlands, England Univ Oxford, Struct Genom Consortium, Oxford OX3 7DQ, Oxon, EnglandMueller, Susanne论文数: 0 引用数: 0 h-index: 0机构: Univ Oxford, Struct Genom Consortium, Oxford OX3 7DQ, Oxon, England Univ Oxford, Struct Genom Consortium, Oxford OX3 7DQ, Oxon, EnglandSchwaller, Juerg论文数: 0 引用数: 0 h-index: 0机构: Univ Basel, Dept Biomed, Lab Childhood Leukemia, CH-4031 Basel, Switzerland Univ Basel, Childrens Hosp, CH-4031 Basel, Switzerland Univ Oxford, Struct Genom Consortium, Oxford OX3 7DQ, Oxon, EnglandStankovic, Tatjana论文数: 0 引用数: 0 h-index: 0机构: Univ Birmingham, Sch Canc Sci, Birmingham B15 2TT, W Midlands, England Univ Oxford, Struct Genom Consortium, Oxford OX3 7DQ, Oxon, EnglandKnapp, Stefan论文数: 0 引用数: 0 h-index: 0机构: Univ Oxford, Struct Genom Consortium, Oxford OX3 7DQ, Oxon, England Univ Oxford, Nuffield Dept Clin Med, Target Discovery Inst, Oxford OX3 7DQ, Oxon, England George Washington Univ, Sch Med & Hlth Sci, Dept Biochem & Mol Biol, Washington, DC 20037 USA Univ Oxford, Struct Genom Consortium, Oxford OX3 7DQ, Oxon, England
- [7] Discovery, structural insight, and bioactivities of BY27 as a selective inhibitor of the second bromodomains of BET proteinsEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 182Chen, Deheng论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China Univ Chinese Acad Sci, 19 Yuquan Rd, Beijing 100049, Peoples R China Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R ChinaLu, Tian论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China Nanjing Univ Chinese Med, 138 Xianlin Rd, Nanjing 210023, Jiangsu, Peoples R China Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R ChinaYan, Ziqin论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R ChinaLu, Wenchao论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China Univ Chinese Acad Sci, 19 Yuquan Rd, Beijing 100049, Peoples R China Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R ChinaLyu, Xilin论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R ChinaXu, Biling论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China Dalian Univ Technol, Sch Life Sci & Med, 2 Dagong Rd, Panjin, Peoples R China Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R ChinaJiang, Hualiang论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R ChinaChen, Kaixian论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China Nanjing Univ Chinese Med, 138 Xianlin Rd, Nanjing 210023, Jiangsu, Peoples R China Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R ChinaLuo, Cheng论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China Nanjing Univ Chinese Med, 138 Xianlin Rd, Nanjing 210023, Jiangsu, Peoples R China Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R ChinaZhao, Yujun论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China Univ Chinese Acad Sci, 19 Yuquan Rd, Beijing 100049, Peoples R China Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China
- [8] The Commonly Used PI3-Kinase Probe LY294002 Is an Inhibitor of BET BromodomainsACS CHEMICAL BIOLOGY, 2014, 9 (02) : 495 - 502Dittmann, Antje论文数: 0 引用数: 0 h-index: 0机构: Cellzome GmbH, D-69117 Heidelberg, Germany Cellzome GmbH, D-69117 Heidelberg, GermanyWerner, Thilo论文数: 0 引用数: 0 h-index: 0机构: Cellzome GmbH, D-69117 Heidelberg, Germany Cellzome GmbH, D-69117 Heidelberg, GermanyChung, Chun-Wa论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Stevenage SG1 2NY, Herts, England Cellzome GmbH, D-69117 Heidelberg, GermanySavitski, Mikhail M.论文数: 0 引用数: 0 h-index: 0机构: Cellzome GmbH, D-69117 Heidelberg, Germany Cellzome GmbH, D-69117 Heidelberg, GermanySavitski, Maria Faelth论文数: 0 引用数: 0 h-index: 0机构: Cellzome GmbH, D-69117 Heidelberg, Germany Cellzome GmbH, D-69117 Heidelberg, GermanyGrandi, Paola论文数: 0 引用数: 0 h-index: 0机构: Cellzome GmbH, D-69117 Heidelberg, Germany Cellzome GmbH, D-69117 Heidelberg, GermanyHopf, Carsten论文数: 0 引用数: 0 h-index: 0机构: Cellzome GmbH, D-69117 Heidelberg, Germany Cellzome GmbH, D-69117 Heidelberg, GermanyLindon, Matthew论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epinova DPU, Stevenage SG1 2NY, Herts, England Cellzome GmbH, D-69117 Heidelberg, GermanyNeubauer, Gitte论文数: 0 引用数: 0 h-index: 0机构: Cellzome GmbH, D-69117 Heidelberg, Germany Cellzome GmbH, D-69117 Heidelberg, GermanyPrinjha, Rabinder K.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epinova DPU, Stevenage SG1 2NY, Herts, England Cellzome GmbH, D-69117 Heidelberg, GermanyBantscheff, Marcus论文数: 0 引用数: 0 h-index: 0机构: Cellzome GmbH, D-69117 Heidelberg, Germany Cellzome GmbH, D-69117 Heidelberg, GermanyDrewes, Gerard论文数: 0 引用数: 0 h-index: 0机构: Cellzome GmbH, D-69117 Heidelberg, Germany Cellzome GmbH, D-69117 Heidelberg, Germany
- [9] GSK973 Is an Inhibitor of the Second Bromodomains (BD2s) of the Bromodomain and Extra-Terminal (BET) FamilyACS MEDICINAL CHEMISTRY LETTERS, 2020, 11 (08): : 1581 - 1587Preston, Alex论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandAtkinson, Stephen J.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandBamborough, Paul论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Platform Technol & Sci, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandChung, Chun-wa论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Platform Technol & Sci, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandGordon, Laurie J.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Platform Technol & Sci, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandGrandi, Paola论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Cellzome GmbH, D-69117 Heidelberg, Germany GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandGray, James R. J.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandHarrison, Lee A.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandLewis, Antonia J.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Platform Technol & Sci, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandLugo, David论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandMessenger, Cassie论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Platform Technol & Sci, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandMichon, Anne-Marie论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Cellzome GmbH, D-69117 Heidelberg, Germany GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandMitchell, Darren J.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandPrinjha, Rab K.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandRioja, Inmaculada论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandSeal, Jon论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandTaylor, Simon论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandThesmar, Pierre论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandWall, Ian D.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Platform Technol & Sci, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandWatson, J.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandWoolven, James M.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Platform Technol & Sci, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, EnglandDemont, Emmanuel H.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England GlaxoSmithKline Med Res Ctr, Epigenet Discovery Performance Unit, Stevenage SG1 2NY, Herts, England
- [10] A Novel Inhibitor of BET Family Bromodomains Demonstrates In Vivo and In Vitro Potency in B-Cell MalignanciesBLOOD, 2015, 126 (23)El-Gamal, Dalia论文数: 0 引用数: 0 h-index: 0机构: Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USA Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USAHing, Zachary A.论文数: 0 引用数: 0 h-index: 0机构: Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USA Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USAMitchell, Shaneice论文数: 0 引用数: 0 h-index: 0机构: Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USA Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USALaFollette, Taylor D.论文数: 0 引用数: 0 h-index: 0机构: Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USA Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USABrennan, Paul J.论文数: 0 引用数: 0 h-index: 0机构: Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USA Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USAFlynn, Joseph M.论文数: 0 引用数: 0 h-index: 0机构: Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USA Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USAJones, Jeffrey A.论文数: 0 引用数: 0 h-index: 0机构: Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USA Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USAAwan, Farrukh论文数: 0 引用数: 0 h-index: 0机构: Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USA Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USAAndritsos, Leslie A.论文数: 0 引用数: 0 h-index: 0机构: Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USA Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USABlachly, James S.论文数: 0 引用数: 0 h-index: 0机构: Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USA Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USAWilliams, Katie论文数: 0 引用数: 0 h-index: 0机构: Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USA Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USAHarrington, Bonnie K.论文数: 0 引用数: 0 h-index: 0机构: Ohio State Univ, Coll Vet Med, Columbus, OH 43210 USA Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USAGoettl, Virginia M.论文数: 0 引用数: 0 h-index: 0机构: Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USA Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USAWoyach, Jennifer A.论文数: 0 引用数: 0 h-index: 0机构: Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USA Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USALehman, Amy M.论文数: 0 引用数: 0 h-index: 0机构: Ohio State Univ, Dept Bioinformat, Ctr Biostat, Columbus, OH 43210 USA Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USAYu, Lianbo论文数: 0 引用数: 0 h-index: 0机构: Ohio State Univ, Dept Bioinformat, Ctr Biostat, Columbus, OH 43210 USA Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USAByrd, John C.论文数: 0 引用数: 0 h-index: 0机构: Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USA Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USALapalombella, Rosa论文数: 0 引用数: 0 h-index: 0机构: Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USA Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USA