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Primary cutaneous Aspergillus fumigatus infection in immunocompetent host
被引:6
|作者:
Mada, Pradeep Kumar
[1
]
Koppel, Daniel Alexander Saldana
[2
]
Al Shaarani, Majd
[3
]
Chandranesan, Andrew Stevenson Joel
[1
]
机构:
[1] Louisiana State Univ, Hlth Sci Ctr Shreveport, Infect Dis, Shreveport, LA 71105 USA
[2] Louisiana State Univ, Hlth Sci Ctr Shreveport, Internal Med, Shreveport, LA 71105 USA
[3] Louisiana State Univ, Hlth Sci Ctr Shreveport, Anat & Clin Pathol, Shreveport, LA 71105 USA
关键词:
skin;
pathology;
exposures;
dermatological;
drugs: infectious diseases;
D O I:
10.1136/bcr-2019-233020
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Primary cutaneous aspergillosis (PCA) occurs through inoculation of fungal spores directly into the skin from the environment through disrupted skin such as in burns, surgery or penetrating trauma patients. Most cases reported in literature were in the immunocompromised, rarely in immunocompetent patients. The characteristic lesion of cutaneous aspergillosis is a black eschar on a red plaque, or nodule at the site of skin injury. The diagnosis of PCA can be made by identifying hyphal forms on routine H&E staining or special stains such as periodic acid-Schiff or Gomori methenamine-silver stains on skin biopsy and by fungal cultures. We report a case of an 80-year-old farmer who developed cutaneous aspergillosis after a surgical procedure without any systemic spread. The diagnosis was made by histopathology and tissue fungal cultures. He was treated with incision and drainage followed by oral voriconazole for 4 weeks; which led to clinical recovery.
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