Synthesis and Application of Polymer-Supported Chiral Bronsted Acid Organocatalysts

被引：105

作者：

Rueping, Magnus ^{[1
]}

Sugiono, Erli ^{[1
]}

Steck, Alexander ^{[2
]}

Theissmann, Thomas ^{[2
]}

机构：

[1] Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany

[2] Goethe Univ Frankfurt, Inst Organ Chem & Chem Biol, D-60438 Frankfurt, Germany

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2010年 / 352卷 / 2-3期

基金：

欧洲研究理事会;

关键词：

BINOL phosphate; heterogeneous catalysis; immobilization; organocatalysis; polymers; ENANTIOSELECTIVE TRANSFER HYDROGENATION; ASYMMETRIC TRANSFER HYDROGENATION; ALPHA-IMINO ESTERS; CATALYZED TRANSFER HYDROGENATION; CINCHONA ALKALOIDS; PHOSPHORIC-ACIDS; METAL-FREE; EFFICIENT; REDUCTION; IMMOBILIZATION;

D O I：

10.1002/adsc.200900746

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A new methodology for the immobilization of chiral Bronsted acids has been developed. The resulting heterogeneous organocatalysts have been employed in multiple consecutive catalysis cycles in the asymmetric organocatalytic transfer hydrogenation. The new catalyst system can not only be easily recovered from the reaction mixture in a tea-bag approach but it can also be easily reused in several catalytic cycles without loss of reactivity and selectivity.

引用

页码：281 / 287

页数：7

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