Central nervous system endothelium in neuroinflammatory, neuroinfectious, and neurodegenerative disease

被引:0
|
作者
Andjelkovic, AV [1 ]
Pachter, JS [1 ]
机构
[1] Univ Connecticut, Ctr Hlth, Dept Pharmacol, Farmington, CT 06030 USA
关键词
CNS microvascular endothelium; endothelial dysfunction; cerebral microvasculature;
D O I
10.1002/(SICI)1097-4547(19980215)51:4<423::AID-JNR2>3.0.CO;2-E
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Accumulating evidence points toward a significant role for the microvascular endothelium in the pathogenesis of several neurologic conditions. This review highlights those biochemical, anatomical, and physiological features of the endothelium thought to be dysfunctional in these disease states, and elaborates on novel treatment modalities that target the endothelium. (C) 1998 Wiley-Liss.
引用
收藏
页码:423 / 430
页数:8
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