Oligosaccharide structures: Theory versus experiment

被引：70
作者：
Imberty, A
机构：
[1] Ctr. Rech. Sur Les Macromolec. Veg., Joseph Fourier Univ., BP53, F., Grenoble
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 1997年 / 7卷 / 05期
关键词：
D O I：
10.1016/S0959-440X(97)80069-3
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Recently, the interdependency of theoretical and experimental approaches in the structure determination of oligosaccharides has been confirmed, More accurate simulations are possible because of the advances in software and computers. Meanwhile, improvements in NMR techniques permit the measurement of numerous structural and dynamical parameters, either for the free state or for carbohydrate ligands bound to receptors. Several crystal structures of isolated or protein-complexed oligosaccharides give new clues for modeling the intermolecular forces that drive the interactions. (C) Current Biology Ltd ISSN 0959-440X
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页码：617 / 623
页数：7
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