Nanoparticles as Potential Novel Therapies for Urinary Tract Infections

被引：25

作者：

Sanchez, Sofia, V ^{[1
,2
,3
]}

Navarro, Nicolas ^{[1
,2
,3
]}

Catalan-Figueroa, Johanna ^{[4
,5
]}

Morales, Javier O. ^{[1
,2
,3
]}

机构：

[1] Univ Chile, Sch Chem & Pharmaceut Sci, Dept Pharmaceut Sci & Technol, Santiago, Chile

[2] Ctr New Drugs Hypertens CENDHY, Santiago, Chile

[3] Adv Ctr Chron Dis ACCDIS, Santiago, Chile

[4] Univ Nacl Cordoba, Inst Farmacol Expt Cordoba IFEC CONICET, Fac Ciencias Quim, Dept Farmacol, Cordoba, Argentina

[5] Univ Catolica Maule, Fac Med, Escuela Quim & Farm, Talca, Chile

来源：

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY | 2021年 / 11卷

关键词：

urinary tract infection therapies; composite materials; antibacterial; antibiofilm; organic nanoparticles; inorganic nanoparticles; ZINC-OXIDE NANOPARTICLES; ESCHERICHIA-COLI; IN-VITRO; SILVER NANOPARTICLES; BIOFILM FORMATION; ANTIBACTERIAL ACTIVITY; GOLD NANOPARTICLES; DRUG-DELIVERY; DIAMOND NANOPARTICLES; ANTIMICROBIAL AGENTS;

D O I：

10.3389/fcimb.2021.656496

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Urinary tract infection (UTI) is one of the most common reasons for antibiotic treatment. Nevertheless, uropathogens are steadily becoming resistant to currently available therapies. In this context, nanotechnology emerges as an innovative and promising approach among diverse strategies currently under development. In this review we deeply discuss different nanoparticles (NPs) used in UTI treatment, including organic NPs, nanodiamonds, chemical and green synthesized inorganic NPs, and NPs made of composite materials. In addition, we compare the effects of different NPs against uropathogens in vivo and in vitro and discuss their potential impact the in the near future.

引用

页数：19

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