Tumid lupus erythematosus occurring following highly active antiretroviral therapy for HIV infection: A manifestation of immune restoration

被引:11
|
作者
Chamberlain, AJ
Hollowood, K
Turner, RJ
Byren, I
机构
[1] Oxford Radcliffe Hosp, Dept Dermatol, Oxford, England
[2] Oxford Radcliffe Hosp, Dept Cellular Pathol, Oxford, England
[3] Oxford Radcliffe Hosp, Dept Genitourinary Med, Oxford, England
关键词
D O I
10.1016/j.jaad.2004.04.020
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Tumid lupus erythematosus (LE) is a relatively rare and only recently recognized subset of chronic cutaneous lupus. We report a case occuring in a male with HIV infection whereby his rash was only unmasked by immune restoration following highly active antiretroviral therapy (HAART). The phenomenon of latent inflammatory or autoimmune disease appearing following HAART is now recognized as the "immune restoration syndrome" and tumid LE has not been reported in this setting previously. Fortunately this variant of Lupus does not result in scarring and is responsive to anti-malarials, allowing continuation of HAART in this patient.
引用
收藏
页码:S89 / S93
页数:5
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