Segmentation and specification in the branchial region of the head: the role of the Hox selector genes

被引：0
|
作者：
Rijli, FM [1 ]
Gavalas, A [1 ]
Chambon, P [1 ]
机构：
[1] Coll France, CNRS INSERM ULP, Inst Genet & Biol Mol & Cellulaire, F-67404 Illkirch Graffenstaden, Strasbourg, France
来源：
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY | 1998年 / 42卷 / 03期
关键词：
homeotic genes; compartments; hindbrain; pattern formation; Hoxa1; Hoxa2;
D O I：
暂无
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Hox genes are segmentally expressed in the developing vertebrate hindbrain, neural crest cells and pharyngeal arches suggesting an important role in patterning these structures. Here we discuss the cellular and molecular mechanisms controlling segmentation and specification in the branchial region of the head. In addition, based on the recent phenotypical and molecular analysis of loss-of-function mutants in the mouse, we speculate that Hox genes may act like Drosophila selector genes in this system.
引用
收藏
页码：393 / 401
页数：9
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