Chemo- and regioselective crossed alkyne cyclotrimerisation of 1,6-diynes with terminal monoalkynes mediated by Grubbs' catalyst or Wilkinson's catalyst

被引：117

作者：

Witulski, B ^{[1
]}

Stengel, T ^{[1
]}

Fernández-Hernández, JM ^{[1
]}

机构：

[1] Univ Kaiserslautern, Fachbereich Chem, D-67663 Kaiserslautern, Germany

来源：

CHEMICAL COMMUNICATIONS | 2000年 / 19期

关键词：

D O I：

10.1039/b005636g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel protocol for crossed alkyne cyclotrimerisations mediated by Grubbs' catalyst [RuCl(2)(=CHPh)(PCy(3))(2)] allows the efficient synthesis of 4,6-substituted indolines with high regioselectivity, and it is complementary to alkyne cyclotrimerisations mediated by Wilkinson's catalyst [RhCl(PPh(3))(3)] allowing the regioselective synthesis of the corresponding 4,5-substituted isomers in many cases.

引用

页码：1965 / 1966

页数：2