Asthma exacerbations in children associated with rhinovirus but not human metapneumovirus infection

被引:122
|
作者
Rawlinson, WD [1 ]
Waliuzzaman, Z
Carter, IW
Belessis, YC
Gilbert, KM
Morton, JR
机构
[1] Prince Wales Hosp, Dept Microbiol, Div Virol, SE Area Lab Serv, Randwick, NSW 2031, Australia
[2] Sydney Childrens Hosp, Dept Resp Med, Randwick, NSW, Australia
[3] Univ New S Wales, Sch Childrens & Womens Hlth, Randwick, NSW, Australia
[4] Univ New S Wales, Sch Med Sci, Fac Med, Kensington, NSW 2033, Australia
[5] Univ New S Wales, Sch Biotechnol & Biomol Sci, Fac Sci, Kensington, NSW 2033, Australia
来源
JOURNAL OF INFECTIOUS DISEASES | 2003年 / 187卷 / 08期
关键词
D O I
10.1086/368411
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Children with asthma were studied during the Southern hemisphere winter and summer of 2001-2002. Human rhinovirus (hRV) was significantly associated (P = .0001) with asthma exacerbations in winter and spring/summer, but not in intervening asymptomatic periods. Although hRV was also found in children with upper respiratory tract infection (URTI) who underwent sampling at the same time, it was present in significantly higher numbers of children with symptomatic asthma (P < .0001). Human metapneumovirus was also found in small numbers of children with URTI, but significantly less frequently in children with asthma.
引用
收藏
页码:1314 / 1318
页数:5
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