Add-back therapy for endometriosis in adolescents

被引:0
|
作者
Lubianca, JN
Gordon, CM
Laufer, MR
机构
[1] Childrens Hosp, Div Gynecol, Dept Surg, Boston, MA 02115 USA
[2] Childrens Hosp, Dept Med, Div Adolescent Young Adult Med & Endocrinol, Boston, MA 02115 USA
[3] Brigham & Womens Hosp, Dept Obstet & Gynecol, Div Reprod Endocrinol, Boston, MA 02115 USA
[4] Harvard Univ, Sch Med, Boston, MA USA
关键词
endometriosis; GnRH; GnRH agonists; adolescence; bone density; add-back therapy;
D O I
暂无
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
OBJECTIVE: To review the impact of gonadotropin-releasing hormone agonists (GnRH-as) an bone mass in adolescents and options for GnRH-a with "add-back" for long-term therapy for adolescents with endometriosis Mot responding to conventional therapy. STUDY DESIGN: Literature research. RESULTS: The use of GnRH-a plus add-back therapy has not been specifically studied in the adolescent population, and thus the ideal dosage of add-back sar steroids for adolescents has not been delineated. CONCLUSION: GnRH-a plus add-back can be considered for usage in adolescents with endometriosis who are refractory to conventional therapy, but steroids due needed to determine the ideal dosage and long-term effects.
引用
收藏
页码:164 / 172
页数:9
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