ORTHOSTATIC MYOCLONUS ASSOCIATED WITH CASPR2 ANTIBODIES

被引：32

作者：

Goevert, Felix ^{[1
]}

Witt, Karsten ^{[1
]}

Erro, Roberto ^{[2
]}

Hellriegel, Helge ^{[1
]}

Paschen, Steffen ^{[1
]}

Martinez-Hernandez, Eugenia ^{[3
]}

Wandinger, Klaus-Peter ^{[4
]}

Deuschl, Guenther ^{[1
]}

Dalmau, Josep ^{[3
,5
,6
]}

Leypoldt, Frank ^{[1
,7
]}

机构：

[1] Univ Kiel, Kiel, Germany

[2] UCL, Inst Neurol, London WC1E 6BT, England

[3] Univ Barcelona, Hosp Clin, August Pi & Sunyer Biomed Res Inst IDIBAPS, E-08007 Barcelona, Spain

[4] Univ Lubeck, Inst Clin Chem, Lubeck, Germany

[5] Univ Penn, Philadelphia, PA 19104 USA

[6] Inst Res & Adv Studies ICREA, Barcelona, Spain

[7] Univ Kiel, Neuroimmunol, Inst Clin Chem, Kiel, Germany

来源：

NEUROLOGY | 2016年 / 86卷 / 14期

关键词：

ENCEPHALITIS;

D O I：

10.1212/WNL.0000000000002547

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Orthostatic myoclonus (OM) is a clinical phenomenon in which myoclonus of the lower limbs appears or becomes worse upon standing.(1) OM usually affects patients older than 65 years and may be a frequent cause of unsteadiness upon standing in the elderly.(2) Although the underlying etiology remains unclear, OM has predominantly been described in association with neurodegenerative diseases.(1) We describe a patient with OM in association with antibodies against contactin-associated protein-2 (Caspr2) whose symptoms markedly improved with immunotherapy.

引用

页码：1353 / 1355

页数：3

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