Leptin-induced decrease in food intake in chickens

被引:130
|
作者
Denbow, DM [1 ]
Meade, S
Robertson, A
McMurtry, JP
Richards, M
Ashwell, C
机构
[1] Virginia Polytech Inst & State Univ, Dept Anim & Poultry Sci, Blacksburg, VA 24061 USA
[2] USDA ARS, Growth Biol Lab, Beltsville, MD 20705 USA
关键词
leptin; food intake; water intake; chickens;
D O I
10.1016/S0031-9384(99)00258-9
中图分类号
B84 [心理学];
学科分类号
04 ; 0402 ;
摘要
The effect of intracerebroventricular (i.c.v.) injection of leptin was investigated using broiler and Single Comb White Leghorn (SCWL)-type chickens. These represent relatively fast- and slow-growing birds, respectively. The i.c.v. injection of leptin decreased food intake in both broilers and Leghorns in a dose-dependent manner. The most efficacious dose appeared to be 10 mu g in both types of chickens. Water intake was generally not affected by leptin, indicating that this effect was not due to general malaise. It appears that leptin can act within the central nervous sytstem of birds to decrease food intake. (C) 2000 Elsevier Science Inc. All rights reserved.
引用
收藏
页码:359 / 362
页数:4
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