Solution structure of a cucurbit[8]uril induced compact supramolecular protein dimer

被引：10
|
作者：
Dang, Dung T. [1 ]
Bosmans, Ralph P. G. [1 ]
Moitzi, Christian [2 ]
Voets, Ilja K. [3 ]
Brunsveld, Luc [1 ,3 ]
机构：
[1] Eindhoven Univ Technol, Dept Biomed Engn, NL-5612 AZ Eindhoven, Netherlands
[2] Anton Paar GmbH, Res & Dev Particle Characterizat, A-8054 Graz, Austria
[3] Eindhoven Univ Technol, Inst Complex Mol Syst, NL-5612 AZ Eindhoven, Netherlands
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2014年 / 12卷 / 46期
关键词：
ANGLE X-RAY; SCATTERING; RECOGNITION; COMPLEXES; DIMERIZATION; SYSTEMS; POLYMERIZATION; STREPTAVIDIN; HEMOPROTEIN; PEPTIDES;
D O I：
10.1039/c4ob01729c
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Supramolecular assembly of a beta-barrel protein via cucurbit[8]uril results in compact z-shaped protein dimers. SAXS data reveal the formation of a well ordered protein dimer, notwithstanding being connected by a reversible and flexible peptide linker, and highlight the supramolecular induced interplay of the proteins, analogous to covalently linked proteins.
引用
收藏
页码：9341 / 9344
页数：4
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